Haematology Flashcards
WhWhat causes acute chest syndrome in sickle cell?
vaso-occlusion in pulmonary microvasculature
infarction of lung parenchyma
How does acute chest syndrome in sickle cell present?
chest pain
dyspnoea
cough
hypoxia
lung infiltrates
What are the different crisis that can occur in sickle cell patients?
acute chest syndrome
aplastic
sequestration
thrombotic
What translocation is seen in CML?
Philadelphia chromosome
t(9;22)
How does nasopharyngeal carcinoma typically present?
otalgia
epistaxis
cervical lymphadenopathy
associated with EBV and members of the east asian community
How do thyroglossal cysts present?
under 20 years old
movement with protrusion of tongue
usually midline
What is the difference between Hodgkins and non-hodgkins lymphoma in terms of blood cells?
Reed-sternberg cells are present in Hodgkins
What is treatment for neutropenic sepsis?
IV piperacillin with tazobactam
What must all patients with Hodgkins lymphoma be given if they require a blood transfusion?
irradiated
If a patient with previous malignancy has a VTE episode?
6 months DOAC
What is 1st line treatment for patients with acute warm haemolytic anaemia?
steroids and rituximab
What is seen in blood film in G6PD?
heinz bodies
What is richters transformation?
CLL to Non hodgkin’s lymphoma
What are the blood test results for DIC?
lower platelets
lower fibrinogen
increased PT and APTT
What to give if a patient is having a non-haemolytic febrile transfusion reaction?
IV/IO paracetamol
