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Year 5 Medicine > Haematology > Flashcards

Haematology Flashcards

1
Q

What haematological condition has increased granulocytes at different stages of maturation?

A

Chronic myeloid leukaemia

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2
Q

What is acute chest syndrome a complication of and how does it present?

A

Sickle cell disease
Dyspnoea, chest pain, cough, hypoxia and new pulmonary infiltrates seen on X-ray

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3
Q

What is the haemoglobin, MCV and reticulocyte combination you would expect in sickle cell disease?

A

Normocytic anaemia
Low HB
Normal MCV
Raised reticulocytes

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4
Q

What condition has auer rods and myeloid blast cells?

A

AML

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5
Q

What test is most useful in diagnosis in polycythaemia vera?

A

JAK2 mutation

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6
Q

What is the treatment for warm autoimmune haemolytic anaemia?

A

Steroids

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7
Q

What is the most common type of Hodgkins lymphoma?

A

Nodular sclerosing

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8
Q

What is the reversal agent for dabigatran?

A

Idarucizumab

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9
Q

What is the first line management of CML?

A

Imatinib

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10
Q

What is the reversal agent for riveroxaban and apixaban?

A

Adexanet alfa

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11
Q

What is the reversal agent for dabigatran?

A

Idarucizumab

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12
Q

What antibiotic increases INR of a patient taking warfarin?

A

Clarithromycin

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13
Q

What is seen on a blood film of hyposplenism?

A

Howell-Jolly bodies

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14
Q

What is raised in patients with beta thalassaemia major?

A

HbA2

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15
Q

When should sickle cell patient have pneumococcal vaccine?

A

Every 5 years

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16
Q

What immunoglobulin deficiency poses a risk for anaphylaxis being more likely in blood transfusion?

A

IgA

17
Q

What blood products are more likely to have bacterial contamination?

A

Platelet concentrate

18
Q

What is heparin overdose treatment?

A

Protamine sulphate

19
Q

What organisms cause post splenectomy sepsis?

A

Strep pneumonia
H. Influenzae
Meningococci

20
Q

What is the treatment for beta thalassaemia major?

A

Life long blood transfusions
Iron chelation therapy

21
Q

What is the most common disease for CLL to turn into?

A

Non-hodgkins lymphoma

22
Q

What are the features of polycythaemia vera?

A

Raised haemoglobin, plethoric appearance, pruritic, splenomegaly, hypertension

Year 5 Medicine (11 decks)

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