Endocrine Flashcards
What is the next step if triple therapy for diabetes not controlled and BMI >35?
Switch one for a GLP-1 mimetic - exenatide
What are results for glucose tolerance test results?
Normal = 0- under 6, 2- under 7.8
Impaired = 0- 6-7, 2- 7.9-11
Diabetic = 0- over 7, 2 - over 11
What can reduce the risk of thyroid eye disease in graves patient?
Smoking cessation
What is the target HbA1C for a patient taking a sulfonylurea?
53 mmol/mol
How would bloods present for De Quervain’s thyroiditis?
Increase T3/T4
Increase ESR/CRP
Decreased uptake of iodine-13
Reduced TSH
Normal thyroid autoantibodies
Mild Leukocytosis
What is the electrolyte abnormality seen in cushings syndrome?
Hypokalaemia metabolic alkalosis
What weeks are OGTT done in pregnancy for BMI>30?
24-28
After statin therapy starting what is reduction in non hdl cholesterol expected?
> 40%
How is diabetes insipidus characterised on blood tests?
High plasma osmolality
Low urine osmolality
What is the main ecg change seen in hypercalcaemia ?
Shortening of QT interval
If osteoporosis in a male what test would you do?
Testosterone level
What is firstline medication for diabetic neuropathy?
Duloxetine
How is Addisons glucocorticoid therapy split across the day?
Majority given in am with remaining in pm
What are the side effects of pioglitazone and gliclazide?
P = worsening heart failure
G = Hypoglycaemia
How do thiazide diuretics affect glucose tolerance?
Worsen - dont give to diabetics
