Endocrine Flashcards

1
Q

What is the next step if triple therapy for diabetes not controlled and BMI >35?

A

Switch one for a GLP-1 mimetic - exenatide

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2
Q

What are results for glucose tolerance test results?

A

Normal = 0- under 6, 2- under 7.8
Impaired = 0- 6-7, 2- 7.9-11
Diabetic = 0- over 7, 2 - over 11

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3
Q

What can reduce the risk of thyroid eye disease in graves patient?

A

Smoking cessation

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4
Q

What is the target HbA1C for a patient taking a sulfonylurea?

A

53 mmol/mol

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5
Q

How would bloods present for De Quervain’s thyroiditis?

A

Increase T3/T4
Increase ESR/CRP
Decreased uptake of iodine-13
Reduced TSH
Normal thyroid autoantibodies
Mild Leukocytosis

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6
Q

What is the electrolyte abnormality seen in cushings syndrome?

A

Hypokalaemia metabolic alkalosis

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7
Q

What weeks are OGTT done in pregnancy for BMI>30?

A

24-28

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8
Q

After statin therapy starting what is reduction in non hdl cholesterol expected?

A

> 40%

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9
Q

How is diabetes insipidus characterised on blood tests?

A

High plasma osmolality
Low urine osmolality

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10
Q

What is the main ecg change seen in hypercalcaemia ?

A

Shortening of QT interval

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11
Q

If osteoporosis in a male what test would you do?

A

Testosterone level

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12
Q

What is firstline medication for diabetic neuropathy?

A

Duloxetine

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13
Q

How is Addisons glucocorticoid therapy split across the day?

A

Majority given in am with remaining in pm

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14
Q

What are the side effects of pioglitazone and gliclazide?

A

P = worsening heart failure
G = Hypoglycaemia

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15
Q

How do thiazide diuretics affect glucose tolerance?

A

Worsen - dont give to diabetics

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16
Q

What medications are used first line to prevent angina attacks?

A

BB or CCB

17
Q

What type of tachycardia is verapamil contraindicated?

A

VT

18
Q

What is firstline treatment for heart failure with reduced ejection fraction?

A

ACE and BB

19
Q
A