Cancer

Question 1

What malignancy is more likely with Schisotosoma Haematobium?

Answer 1

Squamous cell carcinoma of the bladder

Question 2

What is the first most likely site of metastasis in ovarian cancer?

Answer 2

Para-aortic lymph nodes

Question 3

How long after UTI or prostatitis should you wait before doing a PSA?

Answer 3

6 weeks

Question 4

What benefit does epidural post op analgesia compared to other forms of analgesia post bowel surgery?

Answer 4

Faster return of normal bowel function post op

Question 5

How does COCP affect endometrial cancer?

Answer 5

Protective

Question 6

What sign is seen on CT scan in pancreatic cancer?

Answer 6

Double duct sign

Question 7

What would be seen on bone marrow aspirate in multiple myeloma?

Answer 7

Increased number of plasma cells

Question 8

What would be seen on flood film of patient with multiple myeloma?

Answer 8

Rouleaux formation

Question 9

What are bence jones proteins in the urine a sign of?

Answer 9

Multiple myeloma

Question 11

What occupational exposure compound is associated with transitional carcinoma of the bladder and what occupation?

Answer 11

Aniline dye - aromatic amines
Rubber and textile industry

Question 12

What is a poor prognostic factor for ALL?

Answer 12

Male sex

Question 13

Describe the Ann-arbor staging in lymphoma?

Answer 13

1 - only one lymph node
2 - more than one lymph nodes on one side of diaphragm
3 - Both sides of diaphragm
4 - spread beyond lymph nodes

Question 14

What risk factor of testicular cancer makes it 3 times more likely?

Answer 14

Infertility

Question 15

What symptoms of Hodgkins lymphoma are associated with poor prognosis?

Answer 15

Weight loss> 10% in last 6 months
Fever > 38
Night sweats

Question 16

What cancers are patients at risk of after radiotherapy for prostate cancer?

Answer 16

Bladder, colon and rectal cancer

Question 17

What is the firstline investigation for prostate cancer?

Answer 17

Multiparametric MRI

Question 18

What blood cancer is small mature lymphocytes a sign of?

Answer 18

Chronic lympho

Question 19

What is the score used for histology of prostate malignancy and the number that shows a more aggressive from?

Answer 19

Gleason score 10 - high grade

Question 20

What are cannonball metastases on chest X-ray and what causes it?

Answer 20

Renal cell cancer - balls in the lungs

Question 21

What should be co prescribed for the first three weeks with goserelin?

Answer 21

Cyproterone acetate

Question 22

What ethnic group have a higher incidence of prostate cancer?

Answer 22

Afro-Caribbean

Question 23

What location of oesophageal tumour is likely to be seen with squamous cell carcinoma?

Answer 23

Middle third

Question 24

What type of Hodgkins lymphoma has the worst prognosis?

Answer 24

Lymphocyte depleted

Question 25

What is the treatment for CML?

Answer 25

Imatinib

Question 26

What cancer is associated with tamoxifen use?

Answer 26

Endometrial cancer

Question 27

Which lung cancer has the largest associated with smoking?

Answer 27

Squamous cell

Question 28

What is characteristic on blood film of CLL?

Answer 28

Smear/smudge cells

Question 29

What histology is seen in gastric adenocarcinoma?

Answer 29

Signet ring cells

Question 30

What paraneoplawstic syndrome is associated with non-small cell - squamous lung carcinoma?

Answer 30

Hypertrophic pulmonary osteoarthropathy

Question 31

What type of Hodgkins lymphoma has the best prognosis?

Answer 31

Lymphocyte predominant

Question 32

What is the pathogenesis of burkitt lymphoma?

Answer 32

EBV infection

Question 33

What is the pattern of reticulocytes for sequestrian vs aplastic crisis for sickle cell disease?

Answer 33

Aplastic = reduced reticulocytes
Sequestrian = increased reticulocytes

Question 34

What is associated with tear drop cells on blood film?

Answer 34

Myelofibrosis