Haematological- Thalassemia

Question 1

Def.

Answer 1

• Form of Haemolytic Anaemia
• Hereditary disorder of haemoglobin synthesis.
• Usually in SE Asian, Mediterranean, and
  Indian populations.

Question 2

Radiol Fx.

Answer 2

• Osteoporosis with “honeycomb” coarse trabecular patterns.
• Generalised cortical thinning and enlarged vascular channels.
• Involves entire skeleton in infants and children.
• Can see Hair on end radiating new bone spicules (d/t marrow hyperplasia)
• vertebral bodies & neural arches showing osteopoenia with thinned cortices and coarsened vertical trabecular patterns (needs to be described as ‘accentuation’ of trabecular patterns. )
• Cardiomegaly (normal = 1/2 width of chest space)
  
  • Also splenomegaly / hepatomegaly