Congenital- Osteopoikilosis

Question 1

Def.

Answer 1

• genetic condition (autosomal dominant) involving remodelling of spongy bone -> caused by mechanical stresses.
• small foci that fail to become cancellous

Question 2

Radiol Fx.

Answer 2

• Juxtaarticular small round or ovoid radio-opacities (pathognomonic).
• Epiphyseal and metaphyseal regions affected.
• Symmetric involvement: predilection for long bones, carpal and tarsals.
• Occurs: ilium, scapula, glenoid.
• > Rarely in skull, spine ribs or clavicles.

N.B. -> DDx: blastic metastatic, tuberous sclerosis.