Haematological- Sickle Cell An.

Question 1

Def.

Answer 1

• almost exclusive to African-American population

* radio Fx only in severe / chronic cases

Question 2

Radiol Fx.

Answer 2

• Small tubular bones:
• soft tissue swelling,
• loss of diaphyseal constriction in medullary cavity.
• possibility of solid periosteal response
• hyper plastic marrow formation leading to ‘hair on end’ appearance (can be confused with spiculated periosteal response, but far more widespread)
• Spine commonest viewed area with:
  
  • prominent osteoporosis with accentuated vertical trabeculae.
  • Thinned cortices with appearance of “fish” vertebrae or if vertebral body collapse “H” vertebrae. (d/t lack of blood supply to superior and inferior aspects of vert body)
  • displays ‘Exuberant Sclerosis’ in middle vert body