Haem Tx

Question 1

Describe the treatments for the following types of NHL [3] (in both local and advanced stages diseases)
- Diffuse large B cell lymphoma (DLBCL) [2]
- Follicular lymphoma [2]
- Burkitt’s lymphoma [1]

Answer 1

Diffuse large B cell lymphoma (DLBCL):
* Limited stage disease: R-CHOP; Combined modality therapy (CMT) may be used where chemoimmunotherapy is combined with radiotherapy.
* Advanced stage disease: Treatment may involve R-CHOP or other regimens such as (da)-EPOCH-R.

Follicular lymphoma:
- Limited stages: local radiotherapy
- Advanced disease: immunotherapy with rituximab if asymptomatic. If
symptomatic: RCHOP

Burkitt’s lymphoma
- Intensive chemotherapy