Gyne Cancers Flashcards

1
Q

Most common gynecological cancer in developed countries

A

endometrial cancer

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2
Q

Type of endometrial CA that includes Grade 1 and 2 are estrogen sensitive and
carry a good prognosis

A

Type 1 (80%)

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3
Q

Type of endometrial CA that are grade 3 endometrioid tumors

A

type 2 (20%)

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4
Q

Type of endometrial CA that has a better prognosis than adenosquamous, papillary, serour, or clear cell types

A

endometriod (estrogen sensitive)

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5
Q

How much blood in a menopausal or postmenopausal women require work-up

A

one drop

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6
Q

Presentation includes perimenopausal woman w/irregular vaginal bleeding or postmenopausal woman w/new onset bleeding

A

endometrial CA

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7
Q

Work-up for endometiral CA

A

pelvic exam, urine/serum HCG, Ultrasound

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8
Q

Prevention of endometrial CA

A

progestin w/estrogen, diet/excercise/weight control

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9
Q

Cancer that affects females of all ages

A

ovarian cancer

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10
Q

Most common tissue type of ovarian cancers

A

epithelial (85-90%)

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11
Q

Symptoms include: abdominal distention, abdominal/pelvic pressure, anorexia, nausea, early satiety, dyspnea

A

ovarian cancer

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12
Q

When should you suspect ovarian cancer in women between 40-80yrs?

A

any woman with persistant GI symptoms

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13
Q

Genes that increase risk of ovarian cancer

A

BRCA1 and BRCA2

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14
Q

Markers that can be used in the detection of ovarian cancer

A

CA-125 and HE4

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15
Q

Mean age for cervical cancer

A

47 yrs

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16
Q

Most common type of cervical cancer

A

squamous cell (85-90%)

17
Q

Etiology of cervical cancer

A

oncogenic HPV

18
Q

Screening for cervical cancer

A

pap smear

19
Q

Percentage of sexually active women who will aquire HPV

A

80%. Most will be cleared in 12-18 months

20
Q

Oncogenic types of HPV

A

16, 18, 45

21
Q

What are non-oncogenic types of cervical cancer associated with?

A

formation of condylomata

22
Q

Types of HPV covered by vaccine

A

6, 11, 16, 18

23
Q

Non-oncogenic types of HPV

A

6 and 11

24
Q

Pregnancy category for HPV vaccine

A

category B. okay to give when lactating