Gynae

Question 1

What is RMI score in ovarian cancer?

Answer 1

Predicts if ovarian mass is likely to be malignant

RMI = U x M x ca125

Question 2

What are the US features that score on the RMI score?

Answer 2

Septated cyst
Solid areas 
Bilateral lesions 
Ascites 
Intra abdo mets 

Score a point for each feature
U=1 if one feature
U=3 if 2 or more features

Question 3

What is M in the RMI score ovarian cancer?

Answer 3

1= pre meno
3= post meno

Question 4

What RMI score predicts 70-80% chance malignancy?

Answer 4

RMI of over 200

Question 5

Call-Exner bodies are pathognomic of which type of ovarian tumour?

Answer 5

Granulosa cell

Question 6

A patient with cervical cancer relapses after radical chemo RT. What is mgt?

Answer 6

Pelvic exenteration ONLY for relapse confined to the cervix and less than 3cm in size

If more than that then use carbo/paclitaxel

Question 7

What is response rate within previously irradiated field for carbo taxol in relapsed cervical cancer?

Answer 7

20%

Question 8

Psamomma bodies

Answer 8

Means serous papillary histology

Question 9

Which IHC distinguishes serous papillary ovary from endometrium?

Answer 9

WT1 positive in ovary

Negative in endometrial

Question 10

Which blood test is elevated in granulosa cell tumour?

Answer 10

Inhibin