Breast Flashcards
1
Q
What EF would make you stop herceptin?
A
40% definitely stop it!
2
Q
Risk of contralat primary BC in average BC patient per year?
A
1%
3
Q
Risk of contralat primary BC in average BRCA carrier?
A
50% in fhe next 25 years
4
Q
Is mucinous histology favourable or unfavourable in breast cancer?
A
Favourable
5
Q
What is TDM1?
A
Antibody complex of emtansine and herceptin
Emtansine is a potent tubulin binder - it’s too toxic to use alone
Used second line in mBC Her2 positive
6
Q
What is lapatinib?
A
TKI Against EGFR and her 2
