GU/GYN Flashcards
R renal artery crosses anterior or posterior to IVC
Posterior!
Anterior to renal calyx
L renal v crosses anterior or posterior to aorta
Anterior
Which renal v can be ligated due to icnreased collaterals
Left renal v
Seminal vesicles are connected to
vas deferens
Spermatic cord structures
testicular artery, pampiniform plexus, vas deferens, cremasteric muscle, ilioinguinal nerve, genital branch of genitofemoral nerve
calcium oxalate stones are increased in pts whop have had what previous surgery
TI resection due to increased oxalate absorption in colon
Struvite stones occur with infections with what bacteria
Proteus mirabilis
Urease producing
Cause staghorn calculi
Uric acid stones are increased in pts with what 3 diseases
ileostomies
gout
myeloproliferative disorders
They are RADIOLUCENT
Which type of stone is radiopaque
Struvite
How to prevent cysteine stones
tiopronin
Stones greater than what size are unlikely to pass
6 mm
1 testicular tumor
seminoma
Seminoma - sensitivity to XRT?
Extremely sensitive
Seminoma with AFP elevation
Shouldn’t be! Treat like non seminomatous
tx for seminoma
orchiectomy and retroperitoneal XRT
Chemo in seminoma - what types and when
Reserved for mets or bulky retroperitoneal disesase
cisplatin, bleomycin, VP-16
90% of non seminomatous testicular CA have what markers
AFP and b-HCG
At what stage do non seminomatous testicular CA receive adjuvant chemo
Stage II or greater
Cisplatin, bleomycin, VP-16
MC site of prostate ca
posterior lobe
most common mets for prostate CA
bone
what are options if intracapsular prostate CA and no mets (T1 and T2)
XRT
OR
radical prostatectomy + pelvic LND (if life span >10 years)
Option for prostate CA with extracapsular invasion or metastatic disease
XRT + androgen ablation with leuoprolide, flutamide or bilateral orchiectomy
Leuprolide MOA
GnRH agonist
Flutamide MOA
testosterone receptor blocker
Stage IA prostate CA found with TURP - tx?
nothing
With prostatectomy, how long should it take for PSA to go to 0?
3 weeks
If it doesnt decrease get bone scan to check for mets
What should worry you in a pt with prostate CA with increased alk phos
mets or extracapsular disease
Most common location for RCC met
lung
Radical nephrectomy takes what organs along with the kidney
adrenal gland
Also fat, Gerotas fascia, and regional nodes
Partial nephrectomy is indicated in RCC if..
pt would require dialysis after nephrectomy (tumor <4 cm, cr > 2.5)
MC tumor in kidney
metastasis from breast CA
RCC paraneoplastic syndromes
renin, erythropoietin, PTHrp, ACTH, insulin
Tx for transitional cell CA of renal ppelvis
radical nephroureterectomy
multifocal and recurrent RCC, renal cysts, CNS tumors, pheochromocytoma
Von Hippel Lindau
T1 bladder CA
muscle wall not involved
Tx for T1 bladder CA
intravesical BCG or transuretheral resection
Tx for T2 or greater bladder CA
cystectomy with ileal conduit, chemo and XRT
Chemo for bladder CA
MVAC - methotrexate, vinblastine, adriamycin and cisplatin
Squamous cell CA of bladder is assoc with wha kind of infection
schistosomiasis
What kind of suture for ureteral trauma repair
absorable (to avoid stone formation)
Where does BPH arise from
transitional zone
MOA of finasteride
5 alpha reductase inhibitors
inhibits conversion of testosterone to dihydrotestosterone which inhibits prostate hypertrophy
What is post TURP syndrome
hyponatremia secondary to irrigation with water, can precipitate seizures from cerebral edema
neurogenic bladder can be caused by a nerve injury above what level
T-12
neurogenic obstructive uropathy (incomplete emptying) caused by nerve injury below what level
T12
Can also occur with APR
Tx of uretropelvic obstruction
Pyeloplasty
Tx of veiscoureteral reflux
prophylactic abx and see if child outgrows it
Surgical tx is reimplantation of ureter with long bladderp ortion
Most common urinary tract abnormality
ureteral duplication
can sometimes see ectopic ureter
MC reason for newborn boy not to urinate
posterior urethral valves
Hypospadias is when urethral opens where
Vewntral
Repair for hypospadias
At 6 months with penile skin - use foreskin so NOOO circumcision in these pts!
Varicocele is worrisome for
Renal cell CA
left gonadal vein inserts into left renal vein – obstructure by renal tumor causes varicocele
Sterile epidydimitis can occur secondary to
Increased abodominal straining
Tx of failure of closure of urachus
Resection of sinus/cyst and closure of bladder, relieve lbladder outlet obstruction
RBC casts seen in
glomerulonmephritis
WBC casts are seen in
pyelonephritis or glomerulonephritis
tx for priapism
aspiration of cprpus cavernosum with diliute epinephrine or phenylephrine
SCC of penis tx
penectomy with 2 cm margin
phimosis found at time of laparotomy tx
dorsal slit
What ligament allows anteversion of uterus
round ligament
what ligament contains uterine vessels
broad ligament
infundibular ligament contains what
ovarian artery, nerve and vein
Can see most pregnancies on US at what stage
6 weeks
CT delivers how many rads
2.5 rad (0.025 Gy)
Fetal pole usually seen with beta HCG at
6000
Gestational sac usually seen with beta HCG at
1500
MC site of ectopic pregnancy
ampullary portion of fallopian tubes
MC site of endometriosis
ovaries
1 primary vaginal CA
squamous cell CA
DES (diethylstilbestrol) can cause what CA?
clear cell CA of vagina
Majority of vulvar CA are what type
squamous cell CA
<2 cm vulvar cA: treatment?
WLE and ipsilateral inguinal node dissection, 2 cm margins
Tx of >2 cm vulvar ca
Stage II or greater
Radical vulvectomy - bilateral labia with bilateral inguinal dissections, postop XRT if close margins <1 cm
worst prognosis ovarian CA
clear cell
ovarian CA stage III
spread throughout abdomen
ovarian CA stage I
one or both ovaries only
tx for ovarian CA
TAH BSO for all stages PLUS plevic and paraaoritc LN dissection omentectomy 4 quadrant washes chemo
chemo for ovarian CA
cisplatin and paclitaxel
what is a krukenberg tumor and what does path show
stomach CA that has metastasized to ovary
pathology classically shows signet ring cells
what is Meiges syndrome
pelvic ovarian fibroma that causes ascites and hydrothorax
MC malignant tumor in female genital tract
endometrial CA
worst prognosis endometrial CA
clear cell
what stages receieve mandatory XRT in endometrial CA
Stage III/IV
Endometrial CA in cervix is what stage
II
Tx of stage I or II endometrial CA
TAH + BSO or XRT
Endometrial CA in vagina, peritoneum and ovary - what stage
III
Cervical CA assoc with what HPV subtypes
16 and 18
Where does cervical CA travel to (what nodes) first
obturator
stage I and IIa cervical CA - what tx?
TAH
stage IIb to IV cervical CA - what tx?
chemo - XRT
Cervical CA in upper 2/3 of vagina, waht stage?
II
Cervical CA in bladder and rectum, what stage?
IV
ovarian cysts in post menopausal patient - what characteristics mandate oophorectomy with intraoperative frozen sections
septated increased vascular flow on doppler solid components OR papillary projections
Tx of abnormal uterine bleeding if <40 years old
clomiphene citrate (anovulation) or GnRH agonists such as leuoprolide (leiomyoma)
markers for granulosa cell tumor
inhibin
presence of AFP with ovarian neoplasm strongly suggests what kind of tumor
endodermal sinus tumor
elevated LDH and ovarian tumor is likely
dysgerminoma