ALIMENTARY Flashcards

1
Q

Greatest RF for bleeding peptic ulcer

A

NSAID use

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2
Q

Current recommendations for antibiotic prophylaxis in clean-contaminated cases where there is preceding biliary colic within 30 days

A

Ancef x 1

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3
Q

In POEM which muscle layer is divided

A

After creating a longitudinal mucosal incision and creating a submucosal tunnel into the proximal stomach, the endoscopist divides the circular muscle layer of the esophagus, leaving the longitudinal layer intact

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4
Q

volume of fluid produced by stomach

A

1500 mL daily

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5
Q

volume of fluid produced by pancreas

A

1000 mL daily

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6
Q

volume of fluid produced by biliary system

A

1000 mL daily

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7
Q

volume of fluid produced from small bowel

A

2000 mL

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8
Q

RF assoc with poorer prognosis/increased recurrence with SCC of the anus

A
  • tumor size > 5 cm
  • > 2/3 involvement of anal canal circumference Additional identified predictors of decreased survival include male sex, presence of nodal disease, and hemoglobin less than 13 g/dL.
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9
Q

what type of calcium deposits should prompt you to consider prophylactic cholecystectomy in pts with porcelain gallbladder

A

More extensive intramural deposits cause mucosal sloughing, which reduces the rate of adenocarcinoma while the selective calcification yields to a continued inflammatory stimulus. Thus, a stronger recommendation for prophylactic cholecystectomy is made for the selective mucosal calcification pattern in an asymptomatic patient.

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10
Q

best predictor of local recurrence in rectal cancer

A

Initial t stage

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11
Q

Lateral anal fissure should raise concern for

A

Crohn disease, syphilis, anal carcinoma, or tuberculosis.

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12
Q

Nuclear scintigraphy detects acute bleeding at a rate of

A

0.04 mL/minute

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13
Q

Mesenteric angio requires bleeding rate of

A

0.5 mL/minute

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14
Q

An esophageal stricture is refractory if

A

diameter of 14 mm cannot be achieved over 5 sessions at 2-week intervals

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15
Q

An esophageal stricture is recurrent if

A

satisfactory diameter cannot be maintained for 4 weeks once the target diameter of 14 mm has been achieved.

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16
Q

CT angiography can detect bleeding at rates of

A

as low as 0.3 mL/minute, which is better than angiography and only slightly worse than tagged red cell scans.

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17
Q

tagged RBC scan detection rates

A

This method will identify bleeding rates as low as 0.1 mL/minute.

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18
Q

mgmt of “mini GISTs”

A

Tumors that are 1 cm in size are referred to as mini GISTS. These tumors have very low malignant potential and are managed by endoscopic ultrasound surveillance.

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19
Q

High risk features of “mini GIST”

A

High-risk features include the presence of echogenic foci, irregular borders, or ulceration.

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20
Q

Gastric carcinoids occur due to

A

Gastric carcinoids are tumors of the stomach that occur due to hypergastrinemia that occurs with achlorhydria due to proton pump inhibitors.

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21
Q

Mgmt of gastric carcinoid

A

These tumors can be managed by stopping proton pump inhibitors.

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22
Q

Imatinib is used in tx of GIST and what else

A

CML

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23
Q

MC site of internal hernia after Roux en Y

A

Mesojejunal mesenteric window (56%) followed by Petersen defect

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24
Q

Petersen defect

A

mesenteric defect posterior to the roux jejunal limb

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25
surveillance after complete resection of a cancerous polyp with a margin greater than 2 mm.
cscope at 1 year
26
what structure is used to guide the dissection of levator ani muscles from perineum into pelvis
coccyx
27
if pt has previous gastric surgery but requires anti reflux surgery (inadequate fundus for fundoplication)
Hill esophagogastropexy
28
What is hill esophagogastropexy
plication of lesser gastric curvature around right side of esophagus with esophagogastropexy to median arcuate ligaemnt -intraop manometry required
29
slow transit constipation who have failed medical mgmt
total abdominal colectomy with ileorectal anastomosis
30
more than 95% perirectal abscesses arise from
anal glands
31
what is major reason left sided approach is preferred in approach to ecervical esophagus
right RLN has more variable course thus more prone to inadvertent injury
32
bland spindle cells with elongated nuclei
GIST
33
zenkers diverticulum - true or false
false (mucosa and submucosa only)
34
where does zenkers diverticulum occur
area of weakness just superior to cricopharyngeus
35
MC short term complication after roux en y gastric bypass
dehydration (also MC overall)
36
function of secretory IgA
blocks absorption of antigens from the gut
37
nutcracker esophagus - typical amplitude pressures
>180-400 mmHg with long (>6 sec) duration contraction wave
38
high risk GIST
>5 mitosis per HPF or >3 cm
39
what structure should surgeons be cognizant of when dividing gastrohepatic ligament
hepatic breanch of vagus nerve (ligament runs superior to it) also aberrant left hepatic artery
40
cornerstone of initial GOO mgmt
endoscopic dilation and potential H pylori eradiction
41
most excess weight loss procedure
duodenal switch with biliopancreatic diversion
42
selenium deficiency can lead to
cardiomyopathy and weakness
43
vitamin E deficiency
hemolytic anemia | neurologic abnormalities
44
Initial therapy for bowen disease
Topical x like imiquimod
45
Surgical excision for bowen disease - what margins
4 mm low risk | 6 mm high risk
46
corkscrew esophagus on UGI
DES
47
most consistent predictor of good prognosis after hepatic resection in metastatic colon CA
positive response to preop chemotherapy
48
RF that predict poor survival after hepatic resection in metastatic colon CA
``` node positive primary tumor disesase free interval <12 months multiple liver mets largest liver met >5 cm serum CEA >200 ```
49
stenosis of GJ after roux en y most typically occurs after what kind of anastomosis
circular end to end
50
greatest risk of met in GI carcinoid
tumor size <1 cm fewer than 5% will have mets >2 cm most will have mets
51
tx of horseshoe abscess
modified Hanley procedure small incision between tip of coccyx and anal verge, tissues of external sphincter gently separted using a hemostat tto get into the postanal space, abscess is drained, seton placed around sphincter complex and two lateral counterdrainage incisions are made with setons placed in each
52
primary transthoracic operation used to treat GERD
Belsey Mark IV
53
Belsey Mark IV
transthoracic anterior 240 degree plication of fundus buttressed by diaphragmatic crura
54
excess weight loss at 2 years after gastric band
50%
55
truncal vagotomy - what is ligated? pyloric drainage procedure needed?
main trunk of vagus including celiac and hepatic branches | pylorus is denervated --> needs drainage procedure
56
selective vagotomy - what is ligated? pyloric drainage procedure needed?
anterior and posterior gastric nn of Laterjet | pyloric drainage procedure needed
57
highly selective vagotomy aka
parietal cell vagotomy, proximal cell vagotomy
58
tx of pharmacobezoar
activated charcoal
59
tx of phytobezoar
initial try chemical dissolution
60
factors assoc with regression of Barretts
short segment, smoking cessation and PPI use
61
mgmt of low grade dysplasia Barretts
radiofrequency ablation
62
what feature distinguishes IPMN from mucinous cystic neoplasm
communication with pancreatic duct
63
which complications of hemorrhoidectomy are more common in stapled hemorrhoidectomy vs others
tensemus and septic complications and rectal prolapse
64
what is tenesmus s/p hemorrhoidectomy from
likely presence of low rectal suture
65
most common complication of stapled hemorrhoidopexy
early bleeding
66
predictors of response to tx in MALT lymphoma
depth of penetration of gastric wall (deep to mucosa is less responive) absence of AP-12-MALT 1 translocation gastric site (proximal is more worrisome) microsatellite instability advanced age
67
tx for MALT lymphoma after failed response to H pylori tx
XRT with chemo as salvage for XRT failure
68
why are multiple biopsies required in gastric NETs
larger tumors >1 cm can be a/w synchronous gastric adenoCA
69
serum gastrin > what is sensitive and specific for gastric carcinoid
120 pg/mL
70
Choledocho is most likely with bili greater than what level
4 mg/dL
71
surveillance for GB polyp <5 mm
may not be necessary
72
MC site of aortoenteric fistula
duodenum
73
diagnostic modality of choice in hemodynamically abnormal pts with suspected AEF
CTA (sensitivity approaches 94%)
74
chemo for carcinoid and when do you give it
streptozocin and 5FU | unresectable disease
75
tx of flushing in carcinoid syndrome
alpha bl;ockers like phenothiazine
76
what can give false elevation in 5 HIAA
fruits
77
if you perform liver resxn for carcinoid met what else should you do
cholecystectomy in case of future embolization
78
highest sensitivity for detecting carcinoid tumor
chromogranin A level
79
hallmark sx of carcinoid syndrome
intermittent flushing (kallikrein) and diarrhea (serotonin)
80
serotonin produced by
Kulchitsky cells (Enterochromaffin cell or argentaffin cell)
81
Endoscopic classification after esophageal injury with ulcers
2A or B (siperficial vs deep)
82
Endoscopic classification after esophageal injury with necrosis
3A-B | A (focal) B (extensive)
83
next step after noting grade 3 esophageal injury
CT to identify injuries that are nt transmural (camndidates for esophageal preservation)
84
characteristics of high risk malignant polyp
``` poor differentiation lymphovascular invasion submucosal invasion >1 mm margin <1 mm resection in pieces making margin assessment ddifficult ```
85
polyps in stomach that are dome shaped 0.5-1.5 cm
hyperplastic
86
polyps in stomach that are sessile and occur exclusively in the gastric fundus (0.1-0.8 cm)
fundic
87
presence of fundic gland polyps a/w
PPI use hypergastrinemia FAP
88
adenomatous polyps in stomach
may be sessile or polypoid in shape usually <2 cm and solitary can occur spont or as part of familial syndromes such as FAP
89
Tx for esophageal dysmotility in scleroderma
PPI + Reglan
90
Long term CA risk after caustic ingestion
Increased risk of SCC
91
Inner layer of esophagus is what direction and an extension of what
circular inner layer extension of cricopharynxgeus
92
cervical esophagus blood suppl
thyrocervical trunk off subclavian artery (inferior thyroid artery)
93
branches of thyrocervical trunk
STAT Suprascapular artery Transverse cervical artery Ascending cervical artery Inferior thyroid artery
94
Thoracic esophagus arterial supply
branches directly off aorta and branches of bronchial aa
95
ASPECT trial demonstrated that
high dose PPI and ASA chemo prevention therapy especially in combo reduces rate of cancer progression in pts with Barretss
96
Abnormal resting pressure of LES
<6 mmHg
97
Abnormal LES overall length
<2 cm
98
abdominal esophagus blood supply
branches of left gastric nd left inferior phrenic, Belseys, sometimes splenic
99
classic manometry findings for nutcracker esophagus
amplitude pressure >200 mm with long duration (>6 sec) contraction waves
100
Sx of vagal nerve injury after nissen
gastroparesis, delayed gastric emptying, recurrent reflux, diarrhea
101
Killian's triangle
inferior to thyropharyngeus/inferior pharyngeal constrictor and superior to cricopharynxgeus
102
inadequate fundus due to previous gastric surgery
Hill esophagogastropexy Plication of lesser gastric curve around R side of esophagus with an esophagogastropexy to the median arcuate ligament
103
Modified LA Classifcication of Esophagitis: 1+ mucosal break <5 mm in length that does not extend between tops of 2 mucosal folds
Class A
104
Modified LA Classification of Esophagitis: 1+ mucosal break >5 mm that does not extend between the tops of 2 mucosal folds
Class B
105
Modified LA Classification of Esophagitis: 1+ mucosal break that is continuous between tops of 2+ mucosal folds but involves <75% of circumference
Class C
106
Modified LA classification of Esophagitis: 1+ mucosal break that involves at least 75% of circumference
Class D
107
Manometry findings in scleroderma
absent peristaltic contractions with normal or decreased LES
108
T stage of esophageal adenocarcinoma which invades the muscular propria
T2
109
Surgical mgmt for refractory DES
Laparoscopic Heller-for OR a long esophagomyotomy