Group 1 - Morphine Sulfate Flashcards

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1
Q

Morphine Sulfate

Drug Class?

A

Morphine Sulfate Drug Class:

Narcotic agonist

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2
Q

Morphine Sulfate

Mechanism of Action (MOA)?

A

Morphine Sulfate MOA:

  • Elevates pain threshold by acting on the pain receptors in the brain.
  • Depresses CNS, depresses brainstem respiratory centers.
  • Increases venous capacitance, vasodialates arterioles, reducing preload and afterload.
  • Histamine release.
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3
Q

Morphine Sulfate

Indications?

A

Morphine Sulfate Indications:

  • Analgesia
  • Pulmonary edema (Cardiogenic)
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4
Q

Morphine Sulfate

Contraindications?

A

Morphine Sulfate Contraindications:

  • Respiratory depression
  • Head injuries
  • Elevated intracranial pressure
  • Asthma (relative)
  • Abdominal pain (relative)
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5
Q

Morphine Sulfate

Adverse Reactions?

A

Morphine Sulfate Adverse Reactions:

  • CV: Brady/Tachy-dysrhythmias; orthostatic hypotension
  • Resp: Respiratory depression or arrest
  • CNS: Excess sedation, seizures, pupillary constriction
  • Derm: Histamine release may cause local urticaria
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6
Q

Morphine Sulfate

Adult Dose?

A

Morphine Sulfate Adult Dose:

  • 1 - 3 mg increments slow IV push (over 1 - 5 minutes) until desired effect
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7
Q

Morphine Sulfate

Pediatric Dose?

A

Morphine Sulfate Pediatric Dose:

  • 0.1 - 0.2 mg/kg slow IV push
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8
Q

Morphine Sulfate

Onset of Action?

A

Morphine Sulfate Onset of Action:

Seconds

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9
Q

Morphine Sulfate

Peak Effects?

A

Morphine Sulfate

Peak Effects: 20 minutes

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10
Q

Morphine Sulfate

Duration of Action?

A

Morphine Sulfate

Duration of Action: 2 to 4 hours

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11
Q

Morphine Sulfate

AZ Drug Box Minimum Supply?

A

Morphine Sulfate

AZ Drug Box Minimum Supply: 20 mg

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