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microbiology > gram - rods enteric tract > Flashcards

gram - rods enteric tract Flashcards

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Biology 101 flashcards
1
Q

what are enterobacteriaceae located

A

facultative anaerobes in the normal flora of the LI

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2
Q

4 common things of enterobacteriaceae

A

facultative anaerobes, ferment glucose, oxidase negative, convert nitrates to nitrites

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3
Q

enterobacteriaceae antigens

A

O, H, K

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4
Q

enterobacteriaceae endotoxin + or -

A

+

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5
Q

o antigen is an antigenic component of

A

LPS

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6
Q

H antigen is an antigenic component on _____

A

flagellated organisms

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7
Q

K polysaccharide antigen is aka

A

capsular antigen

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8
Q

quellung rxn is with this antigen

A

k polysaccharide

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9
Q

what is K polysaccharide in

A

encapsulated organisms

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10
Q

Vi antigen causes this

A

typhoid fever

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11
Q

most important advances of public health in 20th century

A

disinfection of public water

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12
Q

e coli above ___ is unacceptable in fecal contamination

A

4dL

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13
Q

MCC urinary tract infections and gram - rod sepsis

A

e coli

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14
Q

what dis can e coli cause

A

UTI, sepsis, neonatal meningitis, watery diarrhea, bloody diarrhea

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15
Q

“travlers diarrhea”

A

watery

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16
Q

MCC travelers diarrhea

A

etec- enterotoxin e coli

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17
Q

HUS is mediated by this toxin

A

shiga

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18
Q

EHEC? serotype? acquired where?

A

enterohemorrhagic e coli
O157
acquired in undercooked beef

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19
Q

e coli characteristics

A

straight gram - rod
ferments lactose
OHK antigen

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20
Q

most abundant faculative anaerobe in colon and feces

A

e coli

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21
Q

O55 and O111 cause this

A

neonatal diarrhea

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22
Q

intestinal tract infection of e coli

A

pili attach to jejunum and ileum and make enterotoxins

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23
Q

2 enterotoxins in e coli

A

heat liable toxin (HT)

heat stable toxin (ST)

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24
Q

LT stimulates this

A

adenyl cyclase which inc cAMP and causes watery diarrhea

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25
Q

tell me about enterotoxin strains of e coli (ETEC)

A

dont cause inflammation
dont invade intestinal mucosa
cause watery nonbloody diarrhea

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26
Q

what do shiga toxin producing e coli (STEC) and EHECdo

A

invade epithelium of LI and cause bloody diarrhea (dysentery) and inflammatory cells (neutrophils) in stool

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27
Q

where are shiga toxin producing e coli (STEC) and EHEC found

A

undercooked meats and petting zoos

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28
Q

shiga toxin producing e coli (STEC) and EHEC serologic strains

A

o157:H7

29
Q

HUS has ____ diarrhea

A

bloody

30
Q

HUS consists of…

A

hemolytic anemia, Thrombocytopenia, acute renal failure

31
Q

cranberry juice does what

A

inhibits binding of pili to pyelonephritis associated pili receotors (PAP)

32
Q

pathogenesis of systemic infection e coli

A

capsule and endotoxin

33
Q

what diseases does salmonella cause

A

enterocolitis, enteric fevers like typhoid fever, septicemia like osteomyelitis

34
Q

salmonella antigens

A

O (groups A-I) H (1 and 2) Vi

35
Q

properties of salmonella

A

gram - rod
dont ferment lactose
hydrogen sulfide

36
Q

categories of salmonella

A

typhoidal and nontyphoidal

37
Q

tyhoidal species of salmonella

A

s typhi and s paratyphi

38
Q

nontyphoidal species

A

s enterica

39
Q

transmission salmonella

A

ingesting food/water contaiminated by human wastes

40
Q

MC species of salmonella to cause entercolitis across the US

A

salmonella typhimurium

41
Q

enterocolitis?

A

invasions of epithelial and subepithelial tissue of small and LI

42
Q

salmonella typhimurium is medited by

A

invasins

43
Q

antacids inc chance of infection in

A

enterocolitis

44
Q

enterocolitis trmt

A

self limited, hydration

45
Q

typhoid/enteric fevers transmission in salmonella

A

humans

46
Q

typhoid/enteric fevers in salmonella. where are infections

A

start in SI, few GI sx, organisms enter phagocytes in peyers patches and are carried to other organisms–> bacteremia
typhpoid toxins made in infected cells

47
Q

what happens if bacteria gets in GB in typhoid/enteric fevers in salmonella

A

carrier state

48
Q

typhoid/enteric fevers in salmonella trmt

A

ceftriaxone or cipro

49
Q

s typhi vaccines

A

conjugate- have Vi capsular polysaccharide; give IM

live attenuated- given orally

50
Q

enterocolitis caused by shigella is AKA

A

shigellosis or bacillary dysentery

51
Q

dysnetery?

A

bloody darrhea

52
Q

ingestion of ___ can cause shigella

A

100 orgs

53
Q

shigella properites

A

gram - rod
nonlactose fermenting
o antigen (a, b,c,d)

54
Q

how to distinguish shigella from salmonella

A

no gas from fermentation of glucose
dont make H2S
nonmotile

55
Q

animal reservioir in shigellosis?

A

no

56
Q

transmission shigellosis?

A

fecal oral

57
Q

prolonged carrier state in shigella?

A

none

58
Q

diarrhea type in shigella?

A

bloody

59
Q

shigella pathogenesis

A

shiga toxin invades distal ileum and colon causing bloody diarrhea

60
Q

trmt shigellosis

A

main: fluid and electrolyte replacement

atb if severe

61
Q

vaccine shigellosis

A

none

62
Q

hallmark of cholera

A

watery diarrhea in large volumes, rice water stool

63
Q

cholera toxin

A

cholera toxin

64
Q

ask pt about travel in ____

A

cholera

65
Q

vibrio properties

A

gram - rod
comma shaped
O1 and O139

66
Q

cholera transmission

A

fecal contamination

67
Q

cholera main reserviors

A

marine shellfish, shrimp, oysters

68
Q

trmt cholera

A

rehydration

azithromycin

69
Q

cholera prevention med

A

totracycline

microbiology (13 decks)

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