Gram Negative Cocci

Question 1

Important virulence factors of Neisseria meningitidis

Answer 1

• polysaccharide capsule
• IgA protease
• Endotoxin (shock in meningococcemia)
• pili

Question 2

How can you diagnose gonorrhea?

Answer 2

Gram stain urethral smear (male) ▶️ Gram (-) diplococcus inside PMN
Genetic probes
Thayer-Martin medium

Question 3

Virulence factors of Neisseria gonorrhoeae

Answer 3

Pili ▶️ attachment, Ag variation, (-) phagocytic uptake
Opa proteins ▶️ Ag variation
IgA protease

Question 4

Diseases caused by Moraxella catarrhalis

Answer 4

Otitis media, sinusitis, bronchitis and bronchopneumonia in elderly COPD

Question 5

Which species of gram negative cocci ferment maltose and glucose?

Answer 5

N. meningitidis ▶️ maltose fermenter

N. gonorrhoeae ▶️ glucose fermenter