Gram - Bacilli (Enteric Tract)

Question 1

Enterobacter, Serratia, Klebsiella

Answer 1

ALL 3:
-Pneumona, UTI, multi drug resistant = TX: Carbapenem (like)
-Ferment LACTOSE (pink colonies on Conkey agar)

ENTERO: motile

SERRATIA: motile, red pigment

KLEB: Alcoholics, Abcess, Aspiration
-CAP, cough jelly sputum, UREA POS
-IMMOTILE

Question 2

Salmonella TY and Enter (Non TY)

Answer 2

BOTH:
-MOTILE, H2S + (black colonies)
-CAP, ACID LABILE
-Facultative Intra, M5 (macrophages)

ENTER: undercooked chicken, inflammatory diarrhea, Type 3 rxn

TY: in gallbladder, RED macules, osteomyelitis in SCD, Pea soup diarrhea, live attenuated vaccine

TX: Fluoroquinolones (CIPRO)

Question 3

Shigella

Answer 3

-Green colonies, IMMOTILE
-ACID STABLE (fewer org. to = inf.)
-Bloody stool/diarrhea
-Child = HUS (renal fail), glom. dam., drop in PLT, RBC hemolysis
-Phago M cells, actin filaments, FAC INTRA
-Toxin binds 60S ribs subunit
-Type 3

Question 4

E COLI (ehec/etec)

Answer 4

BOTH
-Ferment LACTOSE (pink)
-Green on EMB AGAR
-CAP, K antigen, CAT POS, Fimbriae (UTIs)
-Gram neg sepsis, meningitis in babies

EHEC: undercooked meat, bloody diarrhea, DOES NOT FERMENT SORBITOL, tox: 60S, HUS, O157:H7 antigen

ETEC: travelers diarrhea (via water, Mex), heat Labile=CAMP, heat Stable=cGMP

Question 5

Yersenia Pestis

Answer 5

-Black Plague
-Trans. via fleas (from rodents)
-BUBOES on skin, Bloody Stools
-Type 3
-Killed vaccine

TX: Aminoglycosides, Tetracycline w. streptomycin

Question 6

Campylobacter Jejuni

Answer 6

-Thermaphilic, trans. via poultry
-BLOODY DIA, Invasive, Reactive Arthritis
-CURVED Gram - ROD
-Oxidase POS
-GUILLAIN BARRE SYND (ASCENDING PARALYSIS)

Question 7

Vibrio Cholera (mainly) - parahaemolyticus, vulnificus

Answer 7

Cholera
-Perfuse watery diarrhea, transmitted via poor san / contam. food or water w. feces
-NOT invasive, Increase CAMP vis GS
-Acid LABILE (grows on alkaline media)
-OX POS

TX: Oral Rehydration w/ Electrolytes

Others: contaminated seafood

Question 8

Helicobacter pylori

Answer 8

-MOTILE, Urea POS, Oxidase POS
-Curved Gram -
-ULCERS (duo) = gastric adenocarcinoma, MALT lymphoma

TX: all 3: PPI / AMOXICILLIN / MACROS (CLARITHROMYCIN)

Question 9

Pseudomonas aeruginosa

Answer 9

-Gram - ROD, OX POS, CAT POS, CAP
-Aquatic env. / OB. AEROBE
-Blue Green pigment, Fruity/Grape smell

SX: pneumonia, pulm. inf. or resp. failure in CF pts
-Burn pts infections
-Osteomyelitis (IVDU/DIA)
-Cath inf (UTIs), Otitis Externa INF
-Lesions (folliculitis or cut. necrosis /black/ etch. gangrenosum)

TOX: EF2 via Ribosylation

TX: Piperacillin / Aminoglycoside / FQ

Question 10

Proteus mirabilis

Answer 10

-Gram - / Swarming Motility
-UREASE POS / Staghorn Caliculi
-Alkaline env. (struvite stone formation)
-UTI w. fishy odor

TX: SULFANAMIDES

Question 11

-Enterobacter, Serratia, Klebsiella =
-Salmonella =
-Shigella =
-E COLI =
-Yersenia Pestis =
-Campylobacter Jejuni =
-Vibrio Cholera =
-Helicobacter pylori =
-Pseudomonas aeruginosa =
-Proteus mirabilis =

Answer 11

= Dinosaurs in Hospital
= Salmon Dinner
= She Gorilla
= E coli’s DINER
= Pet Shop
= Bear Camp
= River Military Scene
= Helicopter scene
= Mona Lisa Tub
= Greek Bathroom God