Gout Flashcards
Gout
Disruption in uric acid metabolism and deposits of urate salts in and around the joints
Gouty Arthritis
Acute and painful inflammation of the joint, one or more. Urate crystals in the synovial fluid
Chronic tophaceous gout
Advanced stage, many years after onset (around 10 years later)
Tophi
What causes Gouty Arthritis
increased uric acid production, decreased uric acid excretion in kidneys or intake of foods containing purine. Two type primary and secondary-drug induced
modifiable risk factors for RA
Hyperuricemia obesity HTN HLD Ischemic cardiovascular disease DM CKD Dietary factors Alcohol Medications altering urate balance
What would Gouty Arthritis look like?
Angry! intense pain, great toe, early in the morning
inflammation, edema, tenderness, redness
Fever, Malaise
When does gouty arthritis peak and resolve
peaks 24-48 hrs and takes 5- 10 days for flare up to resolve
how do we diagnose Gout
serum uric acid- elevated
24 hr urine
synovial fluid
Where is Gout typically found
Great Toe
Tophi are painful and filled with uric acid crystals?
True or False
False Tophi are painless and filled with uric acid crystals
Primary Therapy for acute and chronic therapy
Drug therapy
Acute- Colchicine, relief in 2 day and NSAIDS
Chronic-Prophylactic- allopurinol- 2-6 weeks to see improvement
Gout Collaborative Care
address modifiable risk factors
pain control and joint immobilization during flare up
encourage fluids to maintain increase urine volume to prevent precipitation of uric acid in renal tubules
