Golgi-apparaat Flashcards

1
Q

Functies

A

Rol bij modificatie macromoleculen
Proteolyse van peptiden
Sortering van macromoleculen

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2
Q

Modificatie macromoleculen

A

Toevoeging van suikers
> Vorming van oligosachariden
Macromoleculen afkomstig van RER
Aanmaak van transportblaasjes; omgeven door membraan

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3
Q

Voorkomen Golgi

A

In alle kernhoudende cellen
Soms enkele tientallen per cel
Vaak bij elkaar, dicht bij kern

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4
Q

Onderdelen Golgi

A

Cis-zijde
Trans-zijde
Centraal-mediaal gedeelte

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5
Q

Trans-zijde

A

Rijpe zijde
Vesikels splitsen hiernaartoe af
Opslag/doorvoer

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6
Q

Centrale mediale gedeelte

A

Toevoeging suikers
Hoogste metabole activiteit
Trans-zijde

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7
Q

Cis-zijde

A

Onrijpe zijde
Fosforylatie van eiwitten
Centrale mediale gedeelte

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8
Q

Uitwisseling tussen RER en Golgi

A

Transportvesikel snoert af van RER en fuseert met cis-Golgi-cisterne

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9
Q

Enzymen in cisternen

A

Glycolysering
Sulfatering
Fosforylering
Eiwitsplitsing

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10
Q

Microscopisch beeld

A

Trans-zijde donker
> Condenserende vacuolen
> Secretiegranula (nog donkerder)

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11
Q

Bestemmingen vanaf Golgi

A

Lysosomen
Celmembraan
Extracellulair milieu

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12
Q

Bestemming lysosomen

A

Hydrolytische enzymen

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13
Q

Bestemming celmembraan

A

Membraaneiwitten

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14
Q

Bestemming ECM

A

Secretieproducten

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15
Q

Sleutel bij sortering

A

Mannose-6-fosfaat

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