Gluconeogenesis

Question 0

False about dephosphorylation of fructose 1,6-bisphosphate
A)via hydrolysis
B)fructose 1,6-bisphosphatase
C)Bypasses the irreversible phosphofructokinase-2 reaction
D)Provides an energetically favorable pathway for the formation of fructose 6-phosphate

Answer 0

C)Bypasses the irreversible phosphofructokinase-2 reaction

PFK-1 dapat

Question 1

Which is not a substrate of gluconeogenesis?
A)Amino acids
B)Lactate
C)Glycerol
D)Fatty acids

Answer 1

D)Fatty acids

Question 2

Fructose 1,6-bisphosphatase is stimulated by elevated levels of adenosine monophosphate (AMP) (signal an “energy-poor” state in the cell). True or false?

Answer 2

False.inhibited dapat

Question 3

Fructose 2,6-biphosphate inhibits fructose 1,6-bisphosphatase found in the liver and kidney. True or false?

Answer 3

True

Question 4

False about Hydrolysis of glucose 6-phosphate
A)Bypasses the irreversible hexokinase reaction
B)Provides an energetically favorable pathway for the formation of free glucose
C)done in all organs

Answer 4

C)done in all organs

False. Sa liver and kidney lang ito pwede

Question 5

•*Muscle lacks ___ so they cannot provide blood glucose by gluconeogenesis

Answer 5

Glucose-6-phosphatase

Question 6

•Irreversible reactions of glycolysis are are circumvented by all except:
A.glucose 6-phosphatase
B.fructose 1,6-bisphosphatase
C.pyruvate carboxylase
D.phosphofructokinase

Answer 6

D.phosphofructokinase

This enzyme facilitates an irreversible reaction in glycolysis

Question 7

All are irreversible except:
A.glucose 6-phosphatase
B.fructose 1,6-bisphosphatase
C.pyruvate carboxylase
D.none of the above

Answer 7

D.none of the above

Question 8

In glyceoneogenesis,equilibria of 7 reversible reactions of glycolysis are pushed in favor of glucose synthesis because of the formation of the following except:
A)Phosphoenolpyruvate
B)fructose 6-phosphate
C) glucose
D)ketone bodies

Answer 8

D)ketone bodies

Question 9

All are effects of insulin on gluconeogenesis except:
A)decreased mobilisation of amino acids from muscle protein carbon skeletons for gluconeogenesis
B)decreased transcription of PEP carboxykinase gene
C)decreased availability of PEP carboxykinase activity

Answer 9

A)decreased mobilisation of amino acids from muscle protein carbon skeletons for gluconeogenesis

Increased dapat

Question 10

Acetyl CoA accumulates in increased lipolysis, leading to activation of pyruvate carboxylase. True or false?

Answer 10

True

Question 11

Why does AMP inhibit gluconeogenesis?
A. It activates phosphofructokinase, leading to glycolysis
B. Elevated AMP stimulates pathways for oxidation of nutrients to provide energy for cell
C. Both a and b
D. None of the above

Answer 11

C. Both a and b

Question 12

When glycerol is used as substrate for gluconeogenesis:

◦glycerol -> glycerol phosphate -> ___

Answer 12

Dihydroxyacetone phosphate