Gluconeogenesis Flashcards
1
Q
Location
A
Liver
2
Q
Main source of glucose?
A
Lactate, Pyruvate
3
Q
Cori cycle?
A
Liver gluconeogenesis and muscle glycolysis interconnect
4
Q
Glucose-alanine cycle
A
Liver uses alanine to form glucose to be used by muscle to form alanine…
5
Q
3 irreversible rxns of glycolysis
A
1,3,10
6
Q
Reversed in gluconeogenesis by?
A
10: Pyruvate > OXAC > PEP
- Pyruvate carboxylase(mitochondria), PEPCK(cytoplasm)
3: F-1,6 BisP > F-6-P
- F-1,6 Bisphosphatase
1: G-6-P > Glucose
- G-6-Phosphatase(only in liver)
7
Q
G-6-P > Glucose occurs in?
A
ER lumen
8
Q
RDS?
A
F-1,6 Bisp > F-6-P
9
Q
T/F: Glucagon increases gluconeogenesis in muscle
A
False. No receptor for it in muscle…no effect on glycolysis or gluconeogenesis
10
Q
T/F: Acetyl CoA stimulates binding of biotin in pyruvate carboxylase
A
True
