Glomerulonephritis/nephritic syndrome

Question 1

nephritic syndrome

Answer 1

hematuria, decreased GFR, azotemia, HTN

Question 2

azotemia

Answer 2

increased BUN/Creat

Question 3

Post infectious/acute post streptococcal

Answer 3

kids, acute inflammation from SUBENDO immune complexes, no specific treatment, most recover

Question 4

Post infectious/acute post streptococcal biopsy

Answer 4

IgG/C3 inside glomerulus.

EM: neutrophils in capillary

Question 5

Membranoproliferative GN

Answer 5

chronic, low complement, subendoimmunecomplexes, underlying inflam/immune issue

HEPATITIS

Question 6

Membranoproliferative GN biopsy

Answer 6

proliferative, splitting GM, IgG/C3 stain

Question 7

crescentic

Answer 7

finding, not diagnosis. indicates severe inflammation/cap wall destruction. RAPID KIDNEY LOSS

Question 8

crescentic types

Answer 8

IgG linear (anti GBM disease), IgG granular (immune complex), pouch immune (ANCA+ vasculitis

Question 9

most common crescentic

Answer 9

pauci immune

Question 10

IgG nephropathy/Henoch Schonlein Purpura

Answer 10

HSP” systemic capillaries IgA: glomer only (berger)

recurrent hematuria, ASIA, early onset

Question 11

IgG nephron biopsy

Answer 11

mesangial cell wall expansion, IgA stain

Question 12

Systemic Lupus

Answer 12

lupus nephritis, multiple AB types and complement involved

Question 13

Lupus biopsy

Answer 13

FULL HOUSE