CDK Flashcards
risk factor types
susceptibility (age…) or initiation (HTN, DM…)
classification
CGA: cause, GFR, albuminuria
normal GFR and ALB
> 60 (90) and < 30 albumin to creatinine ratio
proteinuria types
glom injury> albumin in urine
tubular injury> small molecule weight in urine
normal protein filtration
glom blocks large (albumin), small make it through but reabsorbed.
treatment options
block RAS… ACEi dilates efferent, lower PBC, decrease grr but slow progression in the long run of SNGFR loss
sodium in CDK
normal until late, increase excretion (increase FeNa) and decrease absorption. ANP/pressure natures, still HTN
potassium in CKD
control similar to normal, increase load> aldo> excretion, eventually hyperkalemia
metabolic acidosis in CKD
late. limited NH3 production. bone buffer… osteopenia
anemia and CKD
resistance to erythropoietin.. give it! transfuse if we need to
imitation factors
HTN, DM, UTI, autoimmune issues, infections
4 markers of kidney damage
1) proteinuria, 2) abnormalities in the urinary sediment, 3) structural abnormalities seem on imaging, or 4) a tubular disorder
GFR stage 1
> 90
GFR stage 2
60-90
GFR stage 3
30-60
goals of care for GFR stages
diagnose and treat underlying, prevent progression, ID and treat complications, prepare for replacement, start replacement
goals of care for albuminuria stages
diagnose and treat underlying, start ACEi/ARB and lower BP, treat nephrotic or nephritic syndrome
cancer risk in dialysis patients
INCREASED
