glomerulonephritis lecture Flashcards
1
Q
give examples of glomerular disease
A
- diabetic nephropathy
- glomerulonephritis
- amyloid/ light chain nephropathy
- transplant glomerulopathy
2
Q
what are the most common causes of end stage renal failure?
A
- diabetes (first)
- chronic glomerulonephritis (GN)
3
Q
what can acute glomerulonephritis cause?
A
-acute renal failure
4
Q
what is glomerulonephritis?
A
-immune mediates disease of the kidneys affecting the glomeruli
5
Q
what does a proliferative lesion and red cells in urine suggest?
A
-damage to endothelial or mesangial cells
6
Q
what does a non proliferative lesion and protein in urine suggest?
A
-damage to podocytes
7
Q
how is glomerulonephritis diagnosed?
A
clinical presentation
blood tests
kidney biopsy
examination of urine:
- urinalysis (haematuria, proteinuria)
- urine microscopy (RBC, RBC and granular casts, lipiduria)
- urine protein (creatinine ration/24 hour urine)
