Glomerular Diseases and Conditions

Question 1

What are the two Glomerular conditions

Answer 1

Glomerulosclerosis/Nephrosclerosis- Scaring

Glomerulonphritis- Inflamation

Nephrotic Syndrome

Question 2

Glomerulosclerosis/Nephrosclerosis is

Answer 2

Scarring of the glomeruli or Sclerosis- In several conditions of sclerotic such as lupus or diabetes this can occur. it is caused by the activiation of the glomerulal cells produceing scar tissues.

DIABETIC NEPHROPATY is a major cause of this.

Question 3

Acute Glomerulonephritis is

Answer 3

the result of infections. It includes-

Strep infections (impentigo{rarely})

HIV-5-10 % develop kidney failure before fullblown aids

Bacterial endocarditis(infection of the heart)

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Question 4

Symptoms of Glomerular disorders include

Answer 4

• hematuria
• edema (facial/periorbital)
• Azotemia-accumlation of nitrogenous wastes in blood(BUN)
• urine cola colored
• hypertension
• hypoalbuminemia
• ^ BUN & Creatinine
• Headache
• Protienurea, oliguria, dysuria

Question 5

Managment of issues of Glomerular disorders

Answer 5

• Treat S/S such as ^ BP
• Check GFR with 24 hour Creatinine clearance
• Treat Strep infections with antibiotics(PCN penicillin)
• Coriticosteroids(reduce inflamation)
• Limit dietary protiens and increase carbs
• restrict sodium
• If progresses to Chronic condition may be treated as as CKD

Question 6

Complications of Glomerurlar conditions

Answer 6

• Hypertensive Encephalopathy
• Heart Failure(increase in Arthmyias
• Rapid decline in Renal Function can occur to ERSD

Question 7

Nephrotic Syndrome

Answer 7

This is not a specific disease but a set of symptoms that can occur with any disorder of the kidneys,

Question 8

Nephrotic syndrome is:

Answer 8

• a cluster of findings
• a condition of increased Glomerular permeability
• Results in Massive Protien Loss
• Marked increased in protien in urine from loss
  
  • from albumin in urine
  • Foamy urine from protein
• Hypoalbuminemia- low albumin
• Edema(full body) know as Anasarca
• High Serum cholesterol and LDL
• Increased weight from build up of fluids
  *

Question 9

1 liter of fluid is equal to _________ Kilograms or ______lbs

Answer 9

1 Kilogram or 2.2 Lbs

Question 10

Treatment of Nephrotic syndrome includes

Answer 10

• Renal biopsy to determine cause
• Steroids
• immunosupressive agents
• ACE Inhibitors (prils)
• Loop Diuretics
• Statins(which is controversial)
• LIMIT SODIUM INTAKE