GIT 4 Flashcards
What are the Peritoneal spaces
- Subphrenic space
- divided by the falciform ligament into
- right subphrenic space between diaphragm nd liver
- left subphrenic space between diaphragm and spleen
- divided by the falciform ligament into
- Morison’s pouch
- right subhepatic recess
- hepatorenal recess
- most dependent portion of the abdominal cavity and collects fluid
- morisons pouch communicates with the
- lesser sac via the epiploic foramen
- subphrenic space
- right paracolic gutter
- Lesser Sac
- AKA Omental bursa
- posterior to the stomach and anterior to the pancreas
- medial superior extent between lesser curvature and left hepatic lobe, roofed by the gastrohepatic ligament
- access via the epiploic foramen/winslow
- Paracolic gutters
- pelvic
WHAT IS THIS?
histopathology
- Oesophagus is abnormally lined with columnar, metaplastic acid-secreting gastric mucosa.
- It is usually due to chronic reflux oesophagitis.
- Because there is an increased risk of oesophageal cancer, close follow-up and repeated biopsies are recommended
- IMAGING FEATURES
- A reticular mucosal pattern which may be discontinuous in the distal oesophagus (short segment) is the most sensitive finding.
- Suspect diagnosis if there is
- upper or midoesophageal stricture accompanied by reticular mucosal pattern below transition or ulcer
- Low strictures:
- the majority cannot be differentiated from simple reflux oesophagitis strictures and biopsies are required.
https://radiopaedia.org/cases/barrett-oesophagus?lang=gb
Zoomed-in images of the fine reticular pattern superimposed on oesophagitis (fine granular pattern) found in Barrett oesophagus. The area of fine reticulation is either circled in red or pointed to with red arrows.
Thanks to Steve Rubesin MD for this case.
Case Discussion
Biopsy proven Barrett oesophagus (no histologic dysplasia). This is more than an incidental finding on an oesophagram – this is a critical finding. By the time you find a lobulated oesophageal carcinoma it’s too late; the patient needs to be treated and followed at the first signs of metaplasia in the normal oesophageal stratified squamous epithelium.
It is important to get enough air/gas in the oesophagus in order to optimise one’s double contrast technique and pick up subtle findings like this. In addition to effervescent granules, it is often helpful to tell the patient to swallow as much air as possible while drinking the barium.
In this example, the Barrett oesophagus is at the gastro-oesophageal junction, but it can occur in patches anywhere from the mid-oesophagus down to the gastro-oesophageal junction.
DDx of calcified splenic foci on CT
8
- Healed granulomatous disease
- Sarcoid
- TB
- MAI
- Histoplasmosis
- PCP
- Candida
- Treated lymphoma
- Treated Mets
what is this?
who does it tend to occur in?
where does it tend to occur?
DDx?
Desmoplastic small round cell tumor
- aggressive malignancy usually occurring in adolescents and young adults
- CT shows multiple peritoneal-based soft tissue masses with necrosis and hemorrhage.
- Hematogenous or serosal liver mets can be present without a detectable primary tumor
- Desmoplastic small round cell tumours of the peritoneum are a rare and highly aggressive primary peritoneal malignancy.
- Epidemiology
- Desmoplastic small round cell tumour is usually seen in young adolescents and have a male predominance with a mean survival of 2-3 years.
- Clinical presentation
- A desmoplastic small round cell tumour usually presents with a palpable abdominal mass and abdominal distension with discomfort.
- It is most commonly seen to arise from the pelvic peritoneal cavity, the retrovesical or rectouterine space being the most frequent locations. The tunica vaginalis of the testis is the next most common location.
- Solitary or multiple soft tissue masses are seen with no definite organ of origin, usually in the retrovesical or rectouterine space, which enhance heterogeneously on contrast studies. Necrosis, haemorrhage and fibrous components are common.
- Peritoneal seeding, lymph nodal involvement, liver and bone metastases are common modes of spread.
Differential diagnosis
- peritoneal carcinomatosis
- non-Hodgkin lymphoma
- malignant peritoneal mesothelioma
- rhabdomyosarcoma
- See also
- small round blue cell tumours
https://epos.myesr.org/posterimage/esr/ecr2018/143415/mediagallery/753353
What is the Menetrier Disease Triad?
- Large gastric rugal folds (Hypertrophic gastritis), with protein-losing enteropathy.
- Clincial triad of
- Achlorhydria
- hypoproteinemia
- edema
- Typically occurs in middle aged men
- Complications
- gastric carcinoma 10%
- IMAGING FEATURES
- Giant gastric regal folds, usually the proximal half of the stomach
- Hypersecretion
- poor coating
- dilution of barium
- gastric wall thickening
- Small intestinal fold thickening bc of hypoproteinemia
- Peptic ulcers are common
- Case courtesy of Dr Michael P Hartung, Radiopaedia.org, rID: 83761
Gastric Polyps
- Incidence
- Types
- Incidence
- GPs are far less common than colonic polyps
- 2% of all patients with polyps
- Types
-
Hyperplastic Polyps
- 80% of all gastric polyps
- <1cm
- Sessile
- Not premalignant
- A/w
- chronic atrophic gastritis
- Familial adenomatous polyposis (hyperplastic polyps in the stomach, adenomatous polyps in the colon
- typically similar size, multiple, and clustered in the fundus and body.
- Synchronous gastric carcinoma in 5-25% of patients.
- Adenomatous Polyps
- Infrequent
- malignant degeneration 50%
- solitary
- Villous polyps
- uncommon
- cauliflower like
- sessile
- Stong malignant potential
- hamartomatous polyps
- peutz-jeghers
- cronkhite-canada suyndrome
- juvenile polyposis
-
Hyperplastic Polyps
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992058/
What is this?
Caecal bascule
Dr Matt A. Morgan◉ and Assoc Prof Frank Gaillard◉◈ et al.
Caecal bascule is an uncommon type of caecal volvulus in which the caecum folds up over itself in an anteromedial orientation. In contrast to the more common forms of volvulus, there is no axial “twisting” component 4. A caecal bascule may occur in the setting of a large and mobile caecum and can result in closed obstruction involving the caecal pole and appendix.
Clinical presentation and treatment are not significantly different from the more common axial caecal volvulus.
Radiographic features
Plain radiograph
An abdominal radiograph of a patient with a caecal bascule will demonstrate a distended air-filled caecum located centrally within the abdomen. Occasionally the appendix is distended and air-filled, improving one’s confidence that the caecum is obstructed more distally.
Importantly, as the terminal ileum is usually not involved in the volvulus, the small bowel is not obstructed.
Cause of PUD?
- H pylori
- gram negative plays a major role in the development of a peptic ulcer
- Not all people with HP with develop ulcers
- Prevalence of HP: 10% <30yo, 60% of pop >60yo
- Prevalence of HP in DU and GU: 80-90%.
- Risk factor for adenocarcinoma and lymphoma.
- Approach
- precaution against infection should be taken by all GI personnel
- HP serology may become useful from the diagnosis of PUD.
- PUD heal faster with ABx and antacides then with antacids alone.
imaging features of SMA distribution ischaemic bowel disease
sick patients, hypotension, acidosis, high mortality
requeirses surgery, resection
Xray is similarly to SBO, may see pink-prints in SB wall
submucosal edema > pneumatosis > portal vein gas 5%
Symptoms of This?
Signs
Rx.
- Inflammatory eosinophilic esophagitis
- Dysphagia may be chronic, history of allergies, eosinophilia
- Segmental proximal or mid esophageal mild narrowing
- May involve the entire esophagus
- increased risk of iatrogenic tear
- Responds to steroids
What are the most common Peritoneal Metastases?
- Ovarian cancer
- GIT cancer
- Imaging features
- Greater omentum overlying SB “Omental Cake”
- masses on peritoneal surfaces
- Superior surface of sigmoid colon
- POD
- terminal ileum
- morison pouch
- Gastrocolic ligament
- malignant ascities
- May enhance with Gad as a result of increased permeability of peritoneum
Imaging features of Gastritis
- Multiple tiny, apthoid like erosions throught the antrum and boy of the stomach
- Occurs on rugal folds
- Prominent area gastricae
what is the difference between an incarcerated and strangulated hernia?
- Incarceration
- a hernia that cannot be manually reduced
- strangulation
- occlusion of blood supply to the herniated bowel, leading to infarction
- Findings include bowel wall thickening, hemorrhage and pneumatosis as well as venous engorgement and mesenteric edema
Mesenteric panniculitis
- Case courtesy of Dr. Hani Makky Al Salam, Radiopaedia.org, rID: 10092
- A rare disorder characterized by chronic nonspecific inflammation involving the adipose tissue of the SB mesentery.
- When the predominant component is inflammatory or fatty, the disease is called mesenteric panniculitis.
- When fibrosis is the dominant component, the disease is called retractile mesenteritis.
- The latter is considered the final, more invasive stage of mesenteric panniculitis.
- The cause of this condition is unclear.
- Imaging features
- well-circumscribed, inhomogeneous fatty SB mesentery, displaying higher attenuation than normal retroperitoneal fat.
- The mass is usually directed toward the left abdomen where it extends from the mesenteric root to the jejunum.
- Spiculated soft tissue mass, a carcinoid mesenteric mass look-a-like.
What are 2 mimics of an ulcer
- ectopic pancreatic rests may contain a central umbilication that represents a rudimentary duct not ulcer. Commonly located in the antrum.
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298353/
- Gastric diverticulum
- commonly in posterior fundus
- contains mucosal folds, neck
- changes shape during fluoroscopy.
What is this?
What is a complication?
Epiphrenic diverticulum
- May occasionally be recognised on chest radiographs by presence of soft tissue mass.
- Often with an air-fluid level, that mimics a hiatal hernia
- Large diverticulum can compress the true oesophageal lumen, causing dysphagia.
Gastric carcinoma
- Fourth most common GI malignancy
- colon
- pancreas
- liver/bilary
- Stomach
- Risk factors
- pernicious anemia
- adenomatous polyps
- chronic atrophic gastritis
- Billroth II > Billroth I
- Location
- fundus/cardia 40%
- Antrum 30%
- Body 30%
- Staging
- T1:
- limited to mucosa, submucosa
- 5YS 50%
- T2
- Muscle, serosa involved
- 5YS 50%
- T3
- penetration through serosa
- T4
- Adjacent organs involved.
- T1:
- Imaging features
- Features of early gastric cancers
- Polypoid lesions Type 1
- > 0.5cm
- normal peristalsis does not pass through lesions
- difficult to detect radiographically
- Superficial Lesions, Type 2
- 2A <0.5CM
- 2B most difficult to diagnose (mucosal irregularity only).
- 2C 75% of all gastric ca.
- Folds tend to stop abruptly at lesion
- Excavated lesion, Type 3
- malignant ulcer.
- Polypoid lesions Type 1
- Features of early gastric cancers
causes?
Anatomy of this condition
- Causes
- anticoagulant tx
- femoral catheterisation
- trauma
- Appearance
- high-attenuation fluid collection
- first several days +/- fluid level (hc level)
- if there is no further bleeding the high-density RBCs decompose to reduced density fluid
- fluid-fluid level
- Anatomy
- usually confined to the rectus muscle
- About 2cm below the umbilicus (arcuate line), the posterior posterior portion of the rectus sheath disappears and fibers of all three lateral muscle groups (External oblique, internal oblique, and transversus abdominis) passes anterior to the rectus muscle.
- This arrangement has imaging significance in that rectus sheath hematomas above the line are confined within the rectus sheath
- Inferior to the arcuate line, they are directly opposed to the transversal fascia and can dissect across the midline or laterally into the flank (as seen in pic 2)
- Case courtesy of Dr Hani Makky Al Salam, Radiopaedia.org, rID: 9427
USS features of appendicitis
>6mm
noncompressible
>3mm wall thickness
shadowing appendicolith
echogenic periappendiceal fat
Oesophageal Lymphoma
- The oesophagus and stomach do not normally have lymphocytes, primary lymphoma is rare unless present from inflammation’
- secondary metastatic lymphoma is more common.
- Secondary oesophageal lymphoma accounts for <2% of all GIT lymphomas (Stomach > SB)
- Four radiographic presentations are:
- infiltrative
- ulcerating
- polypoid
- endoexophytic
What are the normal oesophageal contour deformities?
- Cricopharyngeus
- Postcricoid impressions (mucosal fold over vein)
- aortic impression
- LMB
- Left atrium
- Diaphragym
- Peristaltic waves
- Mucosa: thin transient transverse folds. Feline Oesophagus. Vs. Thick folds in chronic reflux oesophagitis. Tiny nodules in older adults: glycogenic acanthosis.
What are the two techniques used to percutaneous treat abdominal/pelvic collections
- Trocar technique
- commonly performed for large abscessers or collections with easy access.
- localise abscess by CT or US
- Anesthetize skin
- make skin nick and perforate subcut tissues
- place 8-16Fr abscess drainage catheter in tandem. Remove stylet
- Aspirate all fluid
- send for culture
- wash cavity with saline
- commonly performed for large abscessers or collections with easy access.
- Seldinger technique
- this is commonly performed for abscesses with difficult access or for necrotic tumours with hard rims
- localize abscess
- anesthetize skin
- localize abscess with 4, 6, or 8 inch seldinger or chiba needle (18gauge or 19gauge thin wall) under imaging guidance
- remove needle, leave outer sheath
- pass guide wire through sheath into abscess cavity
- dilate tract (8, 10, 12 Fn) over stiff guide wire
- Remove stiffener and guide wire.
- aspirate abscess
- this is commonly performed for abscesses with difficult access or for necrotic tumours with hard rims
What is this?
traction diverticula: are (true diverticula) which occur secondary to scarring, fibrosis and inflammatory processes (tuberculous adenitis) in the mediastinum pulling on the oesophageal wall
Complications of Gastric ulcers
- Obstruction
- posterior penetration of ulcer into pancreas
- perforation
- bleeding
- filling defect in the ulcer crater may present blood clots
- Gastroduodenal fistula
- double channel pylorus
What is this?
2 types
imaging features
- Diffuse Dysmotility
- Characterised by intermittent chest pain, dysphagia and forceful contractions.
- Diagnosis is diffuse oesohpageal spasm with manometry
- TYPES
- Primary neurogenic abnormality (vagus)
- Secondary reflux oesophagitis
- IMAGING FEATURES
- Nutcracker corkscrew esophagus
- non-specific oesophageal dysmotility disorders
What are the main types of Oesophagitis?
- Esophagitis may present with erosiions, ulcersr and strictures and rarely with perforations and fistulas.
- TYPES
- infectious
- chemical
- Iatrogenic
- Other
- Types in more detail:
- Infectious
- Herpes
- Candidiasis
- CMV
- Chemical
- Reflux oesophagitis
- corrosive (lye)
- Iatrogenic
- radiotherapy
- extended use of NG tubes
- Drugs
- Tetracycline
- NSAIDS
- Potassium
- Iron
- Other
- HIVE
- Scleroderma
- Crohn’s Disease
- Dermatological manifestations
- pemphigoid
- dermatomyositis bullosa
- Infectious
- IMAGING FEATURES
- Thickening and nodularity of oesophageal folds
- Irregularity of mucosa, granularity, ulcerations
- Retraction, smooth tapered luminal narrowing stricture just above the GOJ
HIV Esophagitis. Large ulcers (red, black and white arrows) are seen in these two views of the distal esophagus from an esophagram in a patient with odynophagia and a CD4 count of 30. Biopsies of the ulcers were negative for CMV.
For more information, click on the link if you see this icon
Ddx for appearance of peritoneal metastases
- peritoneal mesothelioma is very similar to peritoneal carcinomatosis, but usually no primary neoplasm is known
-
peritoneal sarcomatosis: if the primary tumour is of mesenchymal origin (i.e. sarcoma)
- most commonly metastases from a gastrointestinal sarcoma 1
-
peritoneal lymphomatosis
- most commonly metastases from a primary (e.g. non-Hodgkin lymphoma) elsewhere 1
-
peritonitis/sepsis
- smooth thickening and enhancement of the peritoneum, with stranding of the omentum and mesentery may be seen in intra-abdominal sepsis
- benign calcifications tend to be sheetlike, and nodal calcifications in these patients less common 2
- a history of peritoneal dialysis or recent abdominal sepsis is usually easily obtained
- peritoneal tuberculosis (image)
How quickly do benign ulcers respond to Rx?
- Benign ulcers decrease 50%in size within 3 weeks and show complete healing withing 6 weeks with successful medical treatment.
- Benign ulcers may heal with local scarring.
AKA
Associations (3)
- Mesenteric Fibromatosis AKA Desmoid Tumour
- Uncommon benign tumour that is locally aggressive, infiltrates adjacent bowel wall and recurs following resection.
- associations
- FAP
- adenomatous polyposis coli (APC) germline mutation.
- asbestosis
- Imaging
- low attenuation on CT
- High sig on T2 MRI
- Case 1 courtesy of Dr Jeremy Jones, Radiopaedia.org, rID: 14806
- Large left-sided abdominal mass with soft-tissue attenuation.
- Mesenteric desmoid tumours are bland fibrous tumours that have an association with familial adenomatous polyposis. In this case, there was no such association with confirmation of histology at percutaneous ultrasound-guided biopsy.
- Case 2 courtesy of Dr James Sheldon, Radiopaedia.org, rID: 41007
- Abdominal mass measures 17 x 8 x 16 cm with regions of cystic degeneration/necrosis within the right side of the mass - the largest low density region measures 4.5 x 5.2 cm.
The mass displaces the bowel to the periphery.
Sections show a core paucicellular fibrous tissue composed of bundles of collagen interspersed with bland stellate fibroblasts and a few small vessels. In immunostains, there is strong nuclear staining for beta-catenin.
DIAGNOSIS: Fibrous tissue suggestive of a desmoid tumour.
Ddx of Splenomegally
- Tumour
- infection
- Meatbolic
- Trauma
- Vascular
- Tumour
- leukemia
- lymphoma
- infection
- Infectious mononucleosis
- histoplasmosis
- HIV
- Meatbolic
- Gaucher disease
- Amyloid
- Hemochromatosis
- Trauma
- Vascular
- Portal hypertension
- Hematologic disorders
- anemia
- sickle cell
- thalassemia
- myelofibrosis
- myelosclerosis
Chagas Disease
What is it?
AKA
What causes it
Mortality rate?
- AKA American Typanosomiasis
- Caused by Trypanosoma cruzi which multiply in the reticuloendothelial system (RES), muscle, and glia cells. When these cells rupture and organisms are destroyed a neurotoxin is released that destroys ganglion cells in the myenteric plexus
- Mortality 5% secondary to myocarditis and encephalitis
DDx of Low density LNs
- Inection
- MAI
- Yersinia
- Sprue/cavitary LN sundrome
- Mets
- Necrotizing mesenteritis
- Whipple Disease
What is this?
- Toxic megacolon (TMC)
- Severe dilation of the trasnverse colon
- when inflammation spreased from the mucosa through other layers of the colon
- aperistaltic
- can perfoated
- 30% mortality
- UC is the most common cause
- CD, Peudomembranous colitis, Ischemic colitis, infectious colitis (CMV, Amebiasis)
- Imaging features:
- >6cm
- ahaustral irregular colonic contour
- may show intraluminal soft tissue masses (pseudopolyps)
- BE is contraindicated. proceed to proctoscopy, gravity maneuvers for plain x-ray assessment.
- diameter of transverse colon should reduce as successful treatment proceeds.
- https://radiopaedia.org/cases/toxic-megacolon-3
Detection and imaging features of PUD
- Detection:
- detection rate of ulcers by double contrast barium is 60-80%
- Imaging features:
- ulcer crater seen en face.
- distinct collection of barium that persists on different views.
- The collection is most often round but can be linear
- ulcer crater seen in profile:
- Barium collection extends outside the projected margin of the gastric or duodenal wall.
- Double contrast studies:
- The crater has a white center with a surrounding black ‘collar’
- Great curvature ulcers are commonly because of malignancy or NSAIDS.
- Multiple ulcers are usually due to NSAIDS
- ulcer crater seen en face.
what is the Carman/Meniscus sign?
The Carman meniscus sign describes the lenticular shape of barium in cases of large and flat gastric ulcers, in which the inner margin is convex toward the lumen. It usually indicates a malignant ulcerated neoplasm; in cases of benign gastric ulcers, the inner margin is usually concave toward the lumen 1.
Carman meniscus sign is seen after compression of a gastric tumour that surrounds the lesser curvature thus apposing both surfaces of the surrounding tumour and entrapping contrast between these margins causing a semilunar configuration 2,3.
The following must be present in order to visualise the sign 3:
flat infiltrating ulcerative lesion with heaped-up margins.
saddle region of the stomach i.e. lesser curvature of body or antrum
examination should be single-contrast or biphasic study (sign may be visible in double contrast study but may be not recognised).
compression must be applied to the stomach.
What is eosinophilic gastroenteritis and what are the
clinical findings and
imaging features?
- Inflammatory disease of unknown causes characterised by focal or diffuse eosinophilic infiltration of the GIT
- an allergic or immunologic disorder is suspected because 50% of patients have another allergic disease
- asthma
- allergic rhinitis
- hay fever
- Only 300 cases have been reported to date
- Rx is with Steroids
Clinical Findings
- abdo pain
- diarrhea
- eosinophilia
Imaging features
- stomach
- tapered antral stensosis (common)
- Pyloric stenosis (common)
- Gastric fold thickening
- SB
- fold thickening (Common)
- Dilatation
- Luminal narrowing
Left lumbar hernia, with omental fat protruding as content is noted. Defect measuring 25 mm in diameter.
There is also protrusion of omental fat through a defect in the left posterior rectus sheath, consistent with an incidental hernia here.
A few non-enhancing simple cortical cysts are seen at both kidneys with maximum diameter of 25 mm. Degenerative changes as osteophytosis are seen at the lumbar spine.
Case Discussion
Left lumbar hernia (Petit hernia).
Additional incidental left posterior rectus sheath hernia
Abdominal COmplications after cardiac Surgery
6
- incidence: 0.2%-2%
- most common complications are related to ischemia
- intraoperative hypotension
- hemorrhage
- vasculopathy
- emboli
- clotting abnormalities
- GI Hemorrhage 50%
- cholecystitis 20%
- emphysematous
- acalculous
- calculous
- Pancreatitis 10%
- Perforated peptic ulcer 10%
- Mesenteric ischemia 5%
- Perforated diverticular disease 5%
Gossypiboma
A gossypiboma, also called textiloma or cottonoid, refers to a foreign object, such as a mass of cotton matrix or a sponge, that is left behind in a body cavity during surgery. It is an uncommon surgical complication. The manifestations and complications of gossypibomas are so variable that diagnosis may be difficult and patient morbidity is significant.