GI Wk 2 Flashcards
HbsAg+
Anti-Hbc+
IgM anti-Hbc negative
Chronic HBV Infection
HbsAg+
Anti-Hbc+
IgM anti-Hbc +
Acutely infected
HbsAg -
Anti-Hbc +
Anti-Hbs +
Immune due to infection
Just Anti-Hbs +
Immune due to vaccine
How long does it take for HbsAg to show up after transmission?
About 4 weeks on average
In a patient without an acute infection, when should they test HbsAg negative?
Around 14 weeks
PPI’s cause which 2 SE’s
HA and Nausea
Promethazine
Phenergan
Phenothiazine class
pANCA antibodies =
Ulcerative Colitis
Which infammatory bowel dz is transmural?
Crohns
NOT smoking makes which IBD worse?
Ulcerative colitis
Smoking makes crohns worse.
Charcots Triad
Of Acute Cholangitis
RUQ pain
Jaundice
Fever and chills
Which IBD had cobblestoning
Crohns
String sign =
Crohns
Murphys sign =
Acute Cholecystitis
Why should porcelain GB be removed?
GB Adenocarcinoma
AMA antibody =
PBC (Primary BIliary Cirrhosis)
ANCA Antibody =
Primary Sclerosing Cholangitis
Drugs to tx Ulcerative Colitis
Sulfasalazine
Mesalazine
Steroids
Skip lesions =
Crohns
Which IBD is more likely to have bloody diarrhea?
Ulcerative Colitis
ASCA Test =
Crohns
IBS is a dx of?
Exclusion
IBS abd pain is relieved by?
defacation
Cholecystitis is usually caused by?
Gallstones
HIDA Scan
Cholescintography
Checks out biliary tree
If GB doesnt fill in HIDA scan, whats the dz?
Obstructive, acute cholelithiases
Abx for acute cholecystitis?
Cipro and Flagyl
Why should porcelain GB be removed?
Risk for GB Adenocarcinoma
What is inflammation of the bile duct system called?
Cholangitis
Primary sclerosing cholangitis is associated with?
Ulcerative colitis
80% crossover
Definitive tx for primary sclerosing cholangitis?
Transplant
Main 2 symptoms of Primary BIliary Cirrhosis
Fatigue and Pruritis
Also Portal HTN
Hyperpigmentation
UDCA is used to tx?
PBC`
Gilberts shows elevation in which liver lab?
Unconjugated BIli (Indirect .Bili)
Bronzing, diabetes and cirrhosis =
Hemochromatosis
Excess of copper in early life =
Wilsons dz
Liver dz and neuropsych
Keiser-Fleicher rings =
Wilsons dz
What is the AST:ALT ratio in alcoholic hepatitis?
Greater than 2
Chronic HBV Tx
Interferon
Which hep causes HCC?
HCV
HCV Tx
Peginterferon
Waterborne RNA Virus
HEV
Encephelopathy Tx
Lower Ammonia Levels with …
Lactulose
Enemas
HDV is associated with?
HBV
85% of all GI bleeds are?
Upper
PUD Most common, then varices, gastritis
Most common site for LGI Hemorrhage?
Colon
Usually diverticulosis
Which component in gluten causes celiacs?
Gliadin
IgA Antibodies to Endomysium
Pathognomonic for Celiacs Dz
Dermititis Herpitiformis
Associated with Celiacs