Gi Tract Flashcards
What do antacids treat
Upper gi disturbances, heart burn, GORD
What are antacids made of
Aluminium and magnesium Salts mixed with other
How do antispasmodics work
. Smooth muscle in intestine relax
. m1&m3 muscle involved
An example anti spasmodic
Meberevic hydrochloride
What does antispasmodic treat
IBS and divticular disease
How do guy morality stimulants work
They are d2 antagonists Increase peristalsis Relax pyloric sphincter Increase osopheogeal sphincter Less build up on sphincter
An example guy morality stimulant
Dompenidone
How do proton pump inhibitors work
. Acidic PH forms two reactive molecules
. Bind permanently to proton pump
. Acid never pump again
An example proton pump
Oneoramzole
How do H2 receptor antagonist work
. Block H2 receptors on partial cells
. Reduce axis production in stomatch
. Block H2 histamine stopping the p.p
An example H2 receptor antagonist
Raidine
How do synthetic prostaglandin E1 work
Protects by preventing acid production and stimulating mucous release
For NSAID ulcer as inhibitors
An example synthetic prostaglandin E1
Misoprostol
How does eradification of h plory work
It is a gram - bacteria in stomatch
During routine ulcer treatments it’s eradicated with triad treatment
How does oral rehydration therapy work
First line
Electrolytes and glucose and water
Small sip
Stimulate absorption
How do anti diarrhoeals work
In the small and large intestine Opoid related . Decrease peristalsis in intestines . Decrease explosive contraction of colon . Kaolin absorb locally
What’s an example anti- diarrhoals
Loperamide
What are the 3 types of laxatives
Bulk forming
Stimulate laxatives
Osmotic
How do bulk forming laxatives work
Increase faecal mass
Stimulate peristalsis
Maintain fluid intake
Days to work
An example bulk forming laxative
Ispaghula husk
How do stimulant laxatives work
Increase peristalsis, stool in large intestine
Used for lazy bowl
An example stimulant laxative
Senna
An example osmotic laxative
Lactulose methylcellulose
Sodium salts
How do osmotic laxatives work
Large sugars magnesium and sodium salts
They’re poorly soluble and draw water to the gut
Easier and softer to pass
