GI Pharm

Question 0

Name two H2 blockers.

Answer 0

Ranitidine, cimetidine.

Question 1

How do H2 blockers work?

Answer 1

Reversibly bind to H2 recptor….. Decrease acid by 90-95%.

Question 2

Side effect of h2 blocker cimetidine?

Answer 2

Gynecomastia

Question 3

How does a PPI work?

Answer 3

Irreversibly binds to enzyme in H2 pump. 99%

Question 4

Name the PPI’s.

Answer 4

Omeprazole, esomeprazole.

Question 5

What is sucralfate and how does it work?

Answer 5

An antacid. Makes a protective gel in the stomach.

Question 6

How does misopristol work as an antacid?

Answer 6

Enhances mucus production. Category X.

Question 7

How does bismuth work as an antacid?

Answer 7

Balances the acid, makes h. Pylori less sticky, can cause black stool and tongue.

Question 8

What is a short term anti diarrheal?

Answer 8

Loperamide.

Question 9

Fibercon is …..

Answer 9

An absorbent anti diarrheal that absorbs water and nutrients and Meds. Not specific.

Question 10

What is a potential side effect of pepto bismal?

Answer 10

ASA toxicity

Question 11

How do bulk forming laxatives work and give an example.

Answer 11

Absorbs h2o into stool. Fiber, psyllium.

Question 12

An emollient laxative use for protection?

Answer 12

Docusate

Question 13

He does miralax work?

Answer 13

It is an hyper osmotic that attracts h2o into intestines.

Question 14

Name a stimulant that works in 1-6 hrs and gives soft stool?

Answer 14

Bisacodyl, senna

Question 15

Name a laxative that gives watery stool in 1-6 hrs.

Answer 15

Golytely, mag citrate.

Question 16

How does compazine, thiazine, and phenergan work?

Answer 16

Block dopamine receptors. SE is drowsiness, bone marrow suppression.

Question 17

Ondansitron is a __________________.

Answer 17

Serotonin antagonist.