GI Flashcards
Schatzki ring
Esophageal stricture
Treatment
Dilation
Zenkers diverticulum
Sxs: dysphagia
Tx: liquid, smaller portions, not usually surgery but can as last resort
Esophageal web
From: Iron deficiency anemia
Triad dysphagia, webs, iron deficiency
Tx: conservative can work, but surgery
Esophageal cancer
60 yo aa alcoholic, smoker or white male with Barrett’s most commonly gets this cancer
Presenting symptom for esophageal cancer
Dysphagia
GERD
Tx: 4 weeks of PPI and lifestyle modifications
EGD only if failed PPI or have alarm symptoms like bleeding, NSAIDs use,
Which antacid avoid in renal failure ?
Ones with mag
Refractory GERD eval
Endoscopy
24 hr ph
Barrett’s esophagus
Risk of adenocarcinoma
If dysphasia , yearly monitoring
Tx:
Peptic ulcer disease
Which more common?
Duodenal 5x more
H. Pylori
Gram negative Bacilis
If PUD and no NSAIDs/Asa, test h.Pylori
Hpylori diagnosis
Urea breath test
H.pylori treatment ?
Amoxicillin 1gm bid
Clarithro 500bid
PPI bid
1 month later when off all meds: repeat urea breath test to see if treated
Ulcer worse with food ?
Better with food?
Gastric worse
Duodenal better
When repeat endoscopy for gastric ulcer?
6-8 weeks after treatment .
Can be more threatening if remain untreated so need to verify
Zollinger Ellison syndrome
Gastric secreting ulcer
Not NSAIDs or h.pylori
Terrible pain
Multiple ulcers
Gastric carcinoma
Over 50 yo
Losing Wt unintentionally, anemic
Vague symptoms
Unconjugated
Indirect
Not water soluble
Preliver bilirubin
Normal stool and urine color
Mild jaundice
Causes : hemolysis or Gilbert’s disease
Gilbert’s disease
Isolated indirect or Unconjugated bilirubin is high. Check direct and it’s just fine.
No treatment needed
Conjugated bilirubin
Anything that blocks
Dark urine / jaundice
Light colored stools
Causes: hepatobiliary problem, biliary obstruction,
Du in Johnson syndrome - benign condition seen in Jewish or w pregnancy or alcohol use
Primary biliary cirrhosis
Vs
Autoimmune hepatitis
Similar
40 yo female
Differentiate by biopsy
Cholelithiasis
Female, fat, forty, fertile, fair, flatulent
Asymptomatic or recurrent epigastric or RUQ abdominal pain, postprandial nausea and +- vomiting
Gastroparesis
Delayed gastric emptying
Tx:
pro motility agent like reglan
Gastric pacer
Better glycemic control
Cholecystitis
Murphys sign, no jaundice
Labs :
Leukocytosis with left shift
Chledocholithiasis
Cholecystitis symptoms
Plus: jaundice and elevated LFTs
Occasionally pancreatitis
Tx: lap chole and ercp together
Cholangitis
Infection of common bile duct or gallstone or tumor blocking it
Charcots triad :
Fever
Jaundice RUQ pain
May have AMS and hypotension
Tx: abx
Primary biliary cirrhosis
45 yo female with fatigue, jaundice, pruritis, mild hepatomegaly.
Elevated alk phos
+ AMA (antmitochondrial antibody)
Dx: liver biopsy
Tx: ursodial , cure–transplant
Autoimmune hepatitis
40 yo female fatigue, arthralgias, jaundice
+ alt/AST
+ ANA / + ASMA
Liver bx. Tx : prednisone/ azothioprine
Primary sclerosing cholangitis
30 yo man typically with IBD or UC with fatigue, jaundice, pruritis, pain
Bad
Chronic inflammation
Fibrosis of bile duct
Elevated TOtal Bili and alk phos