GI Flashcards

1
Q

What artery supplies the transverse colon?

A

Middle colic artery

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2
Q

What artery supplies the ascending colon?

A

Right colic artery

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3
Q

What arteries supply the illeum and jejunum?

A

Jejunal and ileal arteries, arterial arcases and vasa recta

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4
Q

What arteries supplies the illeum, cecum, appendix?

A

Ileocolic artery

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5
Q

What supplies the descending colon?

A

Left colic artery

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6
Q

What supplies the sigmoid colon?

A

Sigmoid artery

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7
Q

Rectum is supplied by:

A

Superior rectal artery

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8
Q

Wht are the portosystemic anastomoses for esophagael varices? and clinical significance?

A

left gastric and azygous vein

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9
Q

What are the portosystemic anastomoses for umbilicus and clinical significance?

A

paraumbilical and inferior epigastric
caput medusa

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10
Q

What are the portosystemic anastomoses for rectum and clinical significance?

A

superior rectal vein–middle and inferior rectal vein
hemorrhoids

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11
Q

Begins digestion of carbohydrates, particularly starches, by hydrolyzing α-1,4 bonds to form disaccharides. It is inactivated by the low pH of the stomach:

A

a- amylase or ptyallin

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12
Q

Begins digestion of lipids; breaks down triglycerides into fatty acids and monoglycerides. It is capable of continued digestion within the stomach. In contrast to pancreatic lipase, it can cleave fatty acids from all three
positions on a triglyceride:

A

lingual lipase

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13
Q

The composition of saliva:

A

high in bicarbonate and potassium
low in Na and cl

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14
Q

What happens at high flow rates of saliva?

A

Ductal cells decrease Na reabsorption and K secretion, however bicorbonate secretion increases.

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15
Q

In low flow rate states, saliva is ________ relative to plasma

A

Hypotonic; with low Na+ and Cl- and high K+

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16
Q

In the first step of the deglutition, what is the purpose of the soft palate?

A

to prevent reflux of into the nasal cavities

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17
Q

In the second step, what constricts and why?

A

Palatopharyngeal folds constrict to only allow allow properly masticated foods to pass

18
Q

Third step of deglutition is?

A

closure of the epiglottis over the trachea

19
Q

What happens to the Upper esophageal sphincter? (4th step)

A

It relaxes in <1 second and peristalsis wave moves bolus to pharynx to esophagus. During this phase breathing is inhibited

20
Q

What controls esophagael phase?

A

Both swallowing and enteric nervous system.

21
Q

What happens during esophagael phase?

A

Movement of the food to the stomach, the lower esophagael sphincters relaxes as a result of vagal stimulation (VIP)

22
Q

What happens to UES after food passes?

A

It contracts to prevent reflux into pharynx

23
Q

What occurs in vomitting reflex?

A

Reverse peristalsis
Stomach and pylorus relaxes
forced inspiration
LES relaxes
Forced expulsion

24
Q

What is secreted in the body of the stomach and what are there functions?

A

Parietal cells- Secrete (H+) and IF- needed for B12 absorption
Chief cells- secrete pepsinogen (protein digestion)

25
Q

What is secreted in the antrum and function?

A

G cells- secrete gastrin, stimulates gastric acid, motility and growth of gastric mucosa
Mucus- secreting cells releases both mucus and bicarbonate
D cells-somatostatin–> inhibits gastrin

26
Q

What is the action of CCK?

A

Breaks down fat. Increases pancreatic secretion, gall bladder contraction, increases sphincter of oddi relaxation, and decreases gastric emptying

27
Q

What is the action of secretin?

A

Releases pancreatic bicarbonate, increases bile secretion and decreases gastric acid secretion.
As bicarbonate increases, Cl- ions decreases because they are exchanged in apical surface

28
Q

What does GLIP do?

A

It decreases gastric H+ secretions, increases insulin release, and decreases gastric emptying
-stimulated when there’s fats, proteins and carbs present

29
Q

Produced by adipose tissue, decreases appetite

A

Leptin

30
Q

What stimulates intestinal water secretion, increases relaxation of smooth muscles and sphincters and counteracts gastrin in the stomach?

A

VIP

31
Q

What produces migratory motor complexes and increases in the fasting state

A

Motilin

32
Q

Alchasia occurs when the LES cannot relax. An increase in LES tone is due to the lost of what?

A

Loss of NO secretion

33
Q

Contractions of the stomach and small intestine during fasting conditions. These contractions occur in a cyclic motor pattern and prevent bacterial overgrowth (housekeeping). They repeat every 90–120 minutes
and are mediated by motilin:

A

Migratory motor complexes

34
Q

Absence of MMC’s lead to:

A

intestinal growth

35
Q

What are oscillating membrane potentials that are stimulated by interstitial cells of cajal and also called gastric slow waves?

A

Basal electric rhythm

36
Q

What has the highest and lowest frequency in BER?

A

Duodenum has the highest and stomach has the lowest

37
Q

Intrinsic factor abosrbs what and where does it occur?

A

Vitamin B12 and the ileum

38
Q

In pancreatic secretion, what ion is higher in low and high rates?

A

low rate- Cl-
High rate - HCO3-

39
Q

Postprandial alkaline tide

A

an increase in bicarbonate in the plasma, and decrease in plasma chloride secondary to the surge of acid within the gastric lumen

40
Q

CO2 + H20 -> H+ and HCO3-

A

this reaction occurs via carbonic anhydrase