GERD pg 2195 Flashcards
difference between pathologic and physiologic GERD?
Pathologic is associated with sx of mucosal injury and often occurs nocturnally.
Pain associated with GERD is secondary to what?
stimulation and activation of mucosal chemoreceptors by acid
what foods exacerbate sx of GERD
spicy, acidic, salty foods and alcohol.
Sx of GERD
heartburn 30-60 mi after meal upon bending or reclining
relief from antacids or baking soda
regurgitation
dysphagia
contributors to dysphagia in GERD patients
erosive esophagitis, abnormal esophageal peristalsis, esophageal stricture.
what are some extraesophageal manifestations of GERD:
asthma
chronic cough
laryngitis
sore throat
non cardiac chest pain
complications of GERD:
barret esophagus. present in 10% of patients with GERD. epithelium cells replaced by metaplastic columnar epithelium containing goblet and columnar cells.
peptic stricture- 5% of patients. progression of solid food dysphagia over months or years. accompanied, usually, with reduction of heartburn sx. located at gastroesophageal junction
when would you use endoscopy with GERD patients?
only complicated cases.
Treatment of GERD:
lifestyle modifications (smaller meals, less acidic foods, fatty foods…etc)
weightloss
avoid lying down 3 hours after meals.
bed on blocks
antacids
treatment of choice for GERD
PPI. (e.g. omeprazole, pantoprazole…)
when should you refer patients with GERD:
no resolution with maximum empiric therapy of 2x a day PPI.
significant dysphagia
barrett esophagus or stricture