Gerd Flashcards
- Q: What percentage of cases with Barrettβs esophagus are familial?
A: A significant portion is familial, though exact percentage varies.
Q: What is gastroesophageal reflux (GER)?
A: Passage of gastric contents into the esophagus with or without regurgitation or vomiting
Q: How is GERD different from GER?
A: GERD involves troublesome symptoms and/or complications of persistent GER, such as esophagitis or stricturing.
What is regurgitation?
A: Effortless movement of stomach contents into the esophagus and mouth.
Q: What percentage of infants under 3 months vomit daily?
A:.
50%
Q: At what age do GER symptoms peak in infants?
A: Around 4 months.
Q: By 12 months, what percentage of infants experience GER symptoms?
A: Only 5%.
Q: Describe the length of the lower esophageal sphincter (LES) in infants.
A: It is very short, less than 1
A: It is more superiorly located in infants than in adults.
What can cause GER in infants?
A: Transient relaxation of the LES and gastric distention from large volume feeds.
Q: What effect does delayed gastric emptying have on GER?
A: It increases the frequency of transient LES relaxations
What role do esophageal clearance and mucosal defense play in GERD?
A: They help prevent esophagitis.
Q: What percentage of pediatric Barrettβs esophagus cases progress to adenocarcinoma?
A: 1-3%.
Q: What percentage of pediatric Barrettβs esophagus cases progress to adenocarcinoma?
A: 1-3%.
Q: Can GERD cause asthma?
A: Yes, through aspiration and vagal-mediated bronchial spasm.
Q: Can asthma cause GERD?
A: Yes, through high negative intrathoracic pressure and LES relaxation.