Genomic Sequencing 1.8 Flashcards
What is genomics
The study of genomes
What is genomic sequencing?
Determines the order (sequence) of nucleotides bases in a section of DNA
What is bioinformatics?
A branch of science which combines statistical analysis and computer technology in order to study and compare sequence data.
What does bioinformatics allow?
The comparison of genomes from different species.
Which genomes are sequenced?
Disease causing organisms
Pest species
Model organisms
Model organisms examples (2)
E.coli - bacterium
Mouse
Similarities between genomes
Genes are highly conserved (similar) across different organisms
Highly conserved genetic sequences can be used in comparisons to..
Establish how close or distant the evolutionary relationship is
SNP stands for
Single nucleotide polymorphisms
What are SNPs
Variations in DNA sequences that effect a single base pair
What is phylogenetics?
The study of evolutionary history and relationships
Diagram used to show evolutionary relationships
Phylogenetic trees
Theory that mutations accumulate at a ____ rate
Constant
Molecular clocks show
When species diverged during evolution by comparing differences in DNA or amino acid sequences.
Three Domains of Life
Bacteria, Archaea and Eukaryotes.