Genetics Flashcards

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1
Q

percentage of variance

A

the fact that individuals vary, an this variability can be partitioned into percentages that are due to different causes

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2
Q

family studies method

A
  • for traits with a large genetic component, the degree of similarity among relatives of that trait will be in proportion to the amount of genetic relatedness/degree of kinship among them
  • ie. you’d be more similar to your siblings (50% shared genetics) than your grandparents (25% shared genetics) on a trait with a high genetic component
  • limitation: similarity observed may also be due to shared environment (ie. your similarity to siblings may just be due to growing up in the same house w/same parents) -> no equal environments assumption
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3
Q

twin studies on mental toughness

A
  • mental toughness: important for academics, achievement, goal attainment, etc. -> involves commitment and control
  • twin studies suggest genetics account for 54% of variance in mental toughness -> genetic and environmental element
  • commitment component demonstrated greatest degree of environmentality -> implications for clinical interventions to increase it
  • showed positive correlation with all Big 5 traits except neuroticism (negative correlation)
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4
Q

adoption studies

A
  • High correlations on traits between adoptive children and adoptive parents provide evidence of environmental influence
  • High correlations between adopted children and genetic parents provide evidence of genetic influence
  • Major strength: genetic parents are providing no environmental influences -> genetics and environment can no longer be confounded
  • Limitation: selective placement (ex. Choosing a child that looks like them; can happen subconsciously) -> confounding of genes/environment
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5
Q

behavioural genetics research on neuroticism and extraversion

A
  • twin studies show that neuroticism and extraversion are very heritable (~50% genetics)
  • adoption studies show slightly less evidence for heritability, and no direct evidence for environmentality (ie. extraverted adoptive parents don’t make their introverted children extroverted)
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6
Q

behavioural genetics research on other traits

A
  • activity level, emotionality, sociability, persistence, fear, distractibility show moderate heritability
  • psychopathic traits show moderate-high heritability
  • aggression shows high heritability
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7
Q

Results from Minnesota Twin Studies

A
  • most traits show modest degree of heritability (including ones we think are highly heritable and highly environmental)
  • some attitudes show heritability (ex. conservatism), but some don’t (ex. religiosity)
  • occupational preference influenced by heritability
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8
Q

sexual orientation

A
  • included as part of personality (though controversially) -> stable over time, associated with different life outcomes
  • heritability varies (30-70%); is typically less than originally thought, but is partly heritable
  • may be due to differences in hypothalamus or a gene on the X chromosome
  • strongly related to childhood gender non-conformity (ie. feminine boys highly likely to be gay men)
  • twins studies show low concordance (probability that if one twin is gay, the other will also be)
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9
Q

what other things are heritable?

A
  • drug use, alcoholism

- likelihood of marriage, divorce, marital quality

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10
Q

influence of shared environmental influenced vs. unshared environmental influences

A
  • Non-shared environments and genetics have much higher influence on personality than shared environments
    • Ex. Correlation of personality traits of adopted siblings (who share environments but not genes) is only .05 -> not causing personality similarities
  • Shared environments tend to influence attitudes, religious beliefs, political orientations, health behaviours, etc. but NOT personality
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11
Q

genotype-environment interaction

A
  • different responses of people with different genotypes to the same environment -> Environment has a different impact depending on the person’s genotype
    • ex. introverts and extroverts responding differently to noisy environments
    • ex. Steve Jobs’ genes predisposed him to high assertiveness and low neuroticism, leading to him recovering after getting fired from Apple and starting a new business rather than withdrawing/failing
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12
Q

genotype-environment correlation (and its 3 sub-types)

A
  • exposure to environmental conditions depends on person’s genotype (ex. a highly intelligent kid might induce his parents to provide more intellectually stimulating environments for him, unlike a less intelligent kid; Steve Jobs’ creativity led him to create Apple)
    • passive gen.corr: seen in early childhood; parents provide genes & environment to kid without any action from kid (ex. buying books for smart kid)
    • reactive gen.corr: parents respond to kids differently based on genotype (ex. kid doesn’t like to be hugged, mom is less physically affectionate with him) -> same as evocation
    • active gen.corr: people seek out environments based on genotype (ex. smart people reading lots of books) -> same as selection
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13
Q

molecular genetics

A
  • methods designed to identify specific genes associated with personality traits
  • ex. association method -> seeing whether individuals with a particular allele/gene are higher or lower in certain traits
  • DRD4 gene is most frequently examined (codes for dopamine receptor, related to novelty-seeking)
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14
Q

environmentalist view

A

personality is determined by socialization processes, such as parenting

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15
Q

nature/nurture vs. person/situation debate

A
  • Nature/person:
    • Person: individual differences or personality characteristics
    • Nature: genetic makeup
  • Nurture/situation:
    • Very similar – environmental and contextual factors
    • Nurture focuses on childhood environment and parenting
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16
Q

nature-nurture debate

A
  • not a debate at the individual level -> what makes us who we are as individuals is ALWAYS a combo of genes and environment
  • This is a question at the group/population level -> ex. Which is more important (genes or environment) in accounting for the differences we see in Trait X?
  • Currently, most experts believe personality is influenced by both nature and nurture; still debate the degree to which biology and environment influence specific behaviours and traits (ex. Sexual orientation, aggression intelligence)
17
Q

insights from human genome project

A
  • Only 2 candidate genes with evidence of influence on personality
    • Dopamine receptor gene DRD4 linked to novelty-seeking (among many psychiatric conditions)
    • Serotonin transporter gene 5-HTTLPR linked to neuroticism and other depressive and anxiety-related traits
  • Conclusion: very many genes involved; no 1-to-1 relationships -> human personality is too complex
18
Q

Genes and traits/behaviour

A
  • Almost everything is partially heritable: self-esteem, personality, IQ, sexual orientation, political & religious orientation, divorce
  • No particular gene for each, but genes influence hormones/arousal, which influences thoughts/feelings, which influences personality
19
Q

heritability

A
  • Proportion of observed variance in group of individuals that can be explained or accounted for by genetic variance
  • Cannot be applied to an individual; not constant or absolute; not a precise statistic
20
Q

environmentality

A
  • Proportion of observed variance in group of individuals attributable to environmental variance
  • Greater the environmentality of a characteristic, the less the heritability
21
Q

twin studies (basics)

A
  • Estimate heritability by gauging whether identical (monozygotic/MZ) twins who share 100% of genes are more similar than fraternal (dizygotic/DZ) twins, who share 50% of genes
  • If MZ twins are more similar than DZ twins, this provides evidence of heritability
  • One way to calculate heritability = Falconer’s Formula (determines proportion of variance due to genetic factors)
22
Q

2 assumptions of twin studies

A
  • Representativeness assumption: twins are representative of the traits in the overall population
  • Equal environments assumption: experiences of two identical twins are not more similar than the overall population
23
Q

heritability estimates of big 5

A
  • Most heritable: openness -> Extraversion -> conscientiousness -> neuroticism & agreeableness
  • Lots of variability of trait heritability within Big 5 traits
24
Q

design that combines strengths of twin and adoption studies

A
  • MZ twins reared apart
  • Neither of them live with biological parents, both adopted separately
  • Look at degree of concordance between a trait – that’s its heritability
25
Q

heritability estimates of big 5 in MZ twins raised apart

A
  • Higher heritability estimates found

- WHY? MZ twin adoption studies allowed estimates to be more precise

26
Q

environmental effects

A
  • shared environmental effects: family and environmental influences that affect twins or siblings similarly (Ex. Parents’ beliefs and attitudes, neighbourhood, number of books in home, time in front of TV, etc.)
  • non-shared environmental effects: family and environmental influences that affect twins or siblings differently (Ex. Birth order, changes in parenting style, unique experiences, etc.)
27
Q

genetic determinism vs. free will

A
  • Do we have conscious control over our actions, thoughts, and personality?
  • free will may be influenced by genetics
  • Ex. Concordance rates of felony convictions are much higher between identical twins than fraternal twins