Genetics 2 Flashcards

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1
Q

What were mendel conclusions

A
  1. For each trait/gene, an individual carries 2 factors (alleles)
  2. Law of segregation
  3. The dominant allele masks the appearance of recessive allele
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2
Q

When do you test cross

A

To determine if unknown genotype is homozygous or heterozygous
Cross is always between a genotypical and homozygous recessive

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3
Q

What is dominant in human blood types

A

A and B are co-dominant over O

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4
Q

What will phenotype look like in co dominance

A

A mix of both alleles

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5
Q

What will phenotypes look like in incomplete dominance

A

A blend of both alleles

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6
Q

Why did T.H. Morgan study fruit flies

A
  1. Reproduce within 2 weeks
  2. Short life span
  3. Produce lots of offspring
  4. Small and easy to keep
  5. Males are easily distinguished from females
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7
Q

What was T.H. Morgan’s conclusion

A

Allele for eye colour is located on the sex chromosomes

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8
Q

Females and males expressing traits on sex-linked traits

A

Females : must receive both alleles to express the trait
Males: must receive only one allele to express the trait
Therefore males are more likely to be diagnosed with hemophilia

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9
Q

What codes one amino acid

A

Sequence of three DNA bases

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10
Q

How are amino acids linked together

A

Polypeptide/peptide (protein)

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10
Q

What many possible genotype in Dihybrid crosses

A

16, 4 gametes from each parents

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11
Q

How do you determine the gametes in Dihybrid crosses

A

F - first
O - outside
I - inside
L - last

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12
Q

What are enzymes involved in

A

The expression of the gene (phenotype)

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13
Q

What are the rules when going from DNA to mRNA

A

G become C
T become A
A become U

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14
Q

Who helps with HGP

A

International collaboration from 2000+ scientists and a private company - celera genomics

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15
Q

What was the goal of human genome project

A

Determine the sequence of DNA N-bases (3 million) found of 23 sets of human chromosomes

16
Q

Examples of manipulating a gene

A

Bacteria is modified to make insulin for diabetics
Corn is modified to be be resistant to insect/pest
Goats are modified to creat spider milk protein in the the milk
Gene therapy is when you replace a dead or with normal gene to cure a disease