Genetic Inheritance Flashcards
Genotype
- Refers to the genes of an individual
- Decides which of a parents two alleles will be inherited by the child
Genes
- Units of heredity
- Carried in DNA
- Code for protien sythesis
Locus
The position of a gene or mutation on a chromosome
Allele
An allele is one of two or more versions of a gene. They can be recessive or dominant
Recessive Alleles
Hidden by dominant allele. Two recessive alleles are needed for the appearance of their resulting trait.
Dominant Alleles
Only one dominant allele needs to be dominant for the appearance of their trait
Why don´t dominant traits always prevail in a population (or why might a recessive trait prevail)?
The alleles on genes may be dominant, but the gene itself might be rarely expressed.
How are dominant alleles expressed?
With a capitol letter
How are recessive alleles expressed?
With a lower case letter
Why might a trait is seen in neither of the parents pop up in a child?
Since humans receive two alleles, (one from each parent) recessive alleles could be present, but not shown as visible traits. If two parents who are heterozygous (Aa [using ´a´ as an example) for a trait have a child, and the allele passed down by each parent is recessive, then the child would homozygous recessive, and therefore show the trait.
Phenotype
The physical appearance of a trait is determined by proteins (gene products). Determined by genotype, because the genotype refers to the genes, and alleles are the specific forms of genes, and whether an allele is recessive or dominant determines a physical trait (aka phenotype)
One trait cross
- Examines the patterns of inheritance of only a single set of alleles for a single characteristic
- Often referred to as monohybrid cross
Two trait cross
- Two trait cross explores the patterns of inheritance of alleles for two different characteristics.
- Also referred to as dihybrid
- (We usually have thousands of trait crosses, but it is too hard to represent that)
Gamete
- Have 23 chromosomes (haploid)
- Diversity is achieved through crossing over
- Gametes combind to form a zygote
Autosomes
- Chromosomes 1-22
-
Autosomal Dominance
- The gene for the trait is carried on the autosome, and one only has to have one allele to express the trait
Autosomal Reccessive
- You need two copies of the recessive gene to express the trait
X linked patterns of inheritance
- genes that are carried on the x chromosome
- x linked dominant means you only mean one gene to inherit the trait
- x linked recessive means you need two genes to inherit the trait
Y linked patterns of inheritance
- genes that are carried on the y chromosome
Pedigrees
- Used to determine patterns of inheritance
- Chart of family history used to predict the likelihood of having a particular gene
- Circles= female
- Squares= male
- Colored shapes= affected induvidual
What phenotype ratio is always observed in a heterozygous x heterozygous dihybrid cross?
9:3:3:1
Autosomes
Chromosomes 1-22
Sex Chromosomes
- Chromosomes that determine one´s gender
Males chromosomes´ XY
Females’ chromosomes´ are XX
Gametes that determine gender
Males: Spermatids (sperm)
Females: Oogocytes (eggs)
X linked genes
Alleles on an X chromosome
Y linked
Alleles on the Y chromosome
X linked disorders
- Disorders found on the X chromosome
- Only males can have Y- linked disorders.
- X linked disorders are more common in men because the men only have to have to get one chromosome (the x) to get the disorder while females have to get 2
- Females can have an X linked disorder
Polygenic Traits
- Controlled by more than one set of alleles
Polygenetic Inheritance
- A trait that is inherited, that requires the inheritance of several genes
Multifactorial Traits
Traits that are subject to multi factors (ex environmental influences)
Pleiotropy
Occurs when a single mutant gene affects two or more distance and seemingly unrelated traits
Incomplete Dominance
Occurs when the heterozygote is intermediate between the two homozygotes
Codominance
Occurs when alleles are equally expressed in a heterzygote
Multiple Alleles
The gene exists in several allelic forms