Genetic, Conception, and fetal development Flashcards

1
Q

three ways people acquire gene mutation that can lead to cancer

A
  1. environment
  2. chance
  3. genetic
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

factors in the environment that causes cancer

A

ultraviolet (UV) light- skin cancer
tobacco smoke - lung cancer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

the second way people acquire mutation

A

by chance.

normal metabolic process can generate chemical that damage DNA.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

the third way people inherit mutation

A

through inheriting mutation gene from their parents

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

two genes that have been recognized as playing a crucial role in the development of cancer

A

oncogene
tumor suppressor genes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what is oncogenes?

A

mutated form of proto-oncogenes.

encourage and promote normal growth and development.

when it becomes carcinogenic, it results in excessive cell multiplication.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

tumor suppressor genes

A

inhibit or put the brakes on the cell growth and division cycle.

prevent development of tumors

mutation cause genes to ignore one or more of the component of network of inhibitory signals removing the brakes from the cell cycle. this results in a rate of uncontrolled growth: cancer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

lynch syndrome

A

aka hereditary nonpolyposis colorectal cancer (HNPCC), is the most common hereditary form of colorectal and uterine cancer

autosomal dominant condition that results from mutations in one of many mismatch repair (MMR) genes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

goal of screening

A

detect or define risk for disease in low-risk populations and identify those for whole diagnostic testing may be appropriate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly