General Pathology C Flashcards

1
Q

Lysosomes may become quite prominent for a number of reasons. One is the need for removal of particles brought into the cell by the process called:
a.Autophagy
b.Heterophagy
c.Pinocytosis
d.Exocytosis

A

Heterophagy

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2
Q

Which of the following is a degenerative lesion?
a.Lipoma
b.Pneumonia
c.Nephrosis
d.Mastitis

A

Nephrosis

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3
Q

This is the most common and most important response to cellular injuries of all types including mechanical, anoxic, toxic, lipid peroxidation, viral, bacterial, and immune mechanisms.
a.Swelling
b.Inclusion bodies
c.Hyalinization
d.Calcification

A

Swelling

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4
Q

This is also called ballooning degeneration.
a.Cloudy swelling
b.Hydropic degeneration
c.Fatty degeneration
d.Hyaline droplet degeneration

A

Hydropic degeneration

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5
Q

The best-known location of fatty degeneration is the:
a.Heart
b.Brain
c.Liver
d.Kidneys

A

Liver

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6
Q

This is a term used to describe the change from normal to variable degrees of smooth eosinophilic appearance in the microscopic examination of tissue.
a.Hyalinized
b.Fibrinoid
c.Amyloid
d.Granulomatous

A

Hyalinized

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7
Q

Xanthomatosis which results from massive accumulation of lipids in macrophages is common in which species?
a.Avian
b.Mammalian
c.Reptilian
d.Amphibian

A

Avian

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8
Q

Calcium in tissues stains _____ with hemotoxylin- eosin.
a.blue
b.black
c.pink
d.green

A

Blue

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9
Q

The term calcinosis is used to describe extensive _____ calcification.
a.Dystrophic
b.Metastatic
c.Idiopathic
d.Pathologic

A

Metastatic

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10
Q

This refers to the condensation of the nuclear chromatin into a dark, round, homogenous mass smaller than a normal nucleus.
a.Karyolysis
b.Karyorrhexis
c.Pyknosis
d.Apoptosis

A

Pyknosis

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11
Q

The following are gross indications of necrosis except:
a.Softening of tissues
b.Definite demarcation between necrotic and viable tissue
c.Dark-colored tissues
d.Presence of a pattern of the lesion

A

Dark-colored tissues

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12
Q

This type of necrosis is manifested by loss of recognizable architecture.
a.Caseation
b.Coagulation
c.Liquefactive necrosis
d.Fat necrosis

A

Caseation

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13
Q

On a cut surface, there are hard white gritty lumps.
a.Fat necrosis
b.Liquefactive necrosis
c.Coagulation
d.Caseation

A

Fat necrosis

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14
Q

The types of gangrene are based on:
a.Color
b.Availability of fluid
c.Severity
d.Pattern

A

Availability of fluid

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15
Q

This refers to the gradual cooling of the body after death.
a.Rigor mortis
b.Algor mortis
c.Imbibation
d.Livor mortis

A

Algor mortis

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16
Q

Anthracosis occurs as a result of inhalation of:
a.Carbon compounds
b.Silica particles
c.Pollen grains
d.Asbestos fibers

A

Carbon compounds

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17
Q

This pigment is found as yellowish-brown granules in the cytoplasm of affected parenchymal cells.
a.Ceroid
b.Lipofuscin
c.Melanin
d.Hemosiderin

A

Lipofuscin

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18
Q

Iron stains ____ in Prussian blue stain.
a.red
b.brown
c.black
d.blue

A

Blue

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19
Q

Heart failure cells are actually:
a.Cardiomyocytes
b.Fibroblasts
c.Alveolar macrophages
d.Endothelial cells

A

Alveolar macrophages

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20
Q

This pigment is very common as ‘formalin pigment’ when unbuffered formalin is used for fixation.
a.Hematin
b.Hemosiderin
c.Bilirubin
d.Hemoglobin

A

Hematin

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21
Q

This test can differentiate conjugated bilirubin from unconjugated bilirubin in the serum.
a.Osmotic fragility test
b.Van den Bergh test
c.Coombs test
d.Schilling test

A

Van den Bergh test

22
Q

The process in which excess blood may be drawn into an area is:
a.hemorrhage
b.hyperemia
c.congestion
d.ischemia

A

Hyperemia

23
Q

This organ is the only source of fibrinogen, prothrombin, and albumin.
a.bone marrow
b.kidneys
c.liver
d.lungs

A

Liver

24
Q

Left-sided heart failure is an example of:
a.Hyperemia
b.Localized congestion
c.Generalized congestion
d.Hypoxia

A

Localized congestion

25
Q

Nutmeg liver is an example of:
a.hyperemia
b.congestion
c.infarction
d.ischemia

A

Congestion

26
Q

A bruise is a result of:
a.hemorrhage
b.hematoma
c.ischemia
d.hyperemia

A

hemorrhage

27
Q

A yellowish tinge in edema fluid indicates:
a.Escape of plasma proteins
b.Presence of bilirubin
c.Infection with bacteria
d.Presence of red blood cells

A

Escape of plasma proteins (edema)

28
Q

Strictly speaking, this refers only to the formation of fibrin:
a.hemostasis
b.coagulation
c.thrombosis
d.fibrinolysis

A

coagulation

29
Q

Which of the following is not a general characteristic of infarcts?
a.Acute
b.Pale colored
c.Ischemic
d.Coagulation necrosis

A

Pale colored

30
Q

This type of shock is usually associated with trauma and loss of fluid in burns.
a.cardiogenic
b.hypovolemic
c.septic
d.neurogenic

A

Hypovolemic

31
Q

This refers to the slowing down of the circulation, settling out of red cells from plasma and increased stickiness of blood.
a.Sludging
b.Disseminated intravascular coagulation
c.Visceral pooling
d.Hypercoagulability

A

Sludging

32
Q

In acute inflammation, neutrophilic exudation is soon followed by ______ exudation.
a.Monocyte
b.Eosinophil
c.Basophil
d.Lymphocyte

A

Monocyte

33
Q

This implies that the bone marrow is not producing cells quickly enough.
a.regenerative shift
b.degenerative shift
c.normoblastic shift
d.hyperplastic shift

A

Degenerative shift

34
Q

Lymphocytes are made in the following except:
a.Tonsils
b.Peyer’s patches
c.Thyroid
d.Liver

A

Thyroid

35
Q

The “bread and butter” appearance of the heart is due to the accumulation of:
a.serous exudate
b.fibrinous exudate
c.purulent exudate
d.catarrhal exudate

A

Fibrinous exudate

36
Q

This is a bodily injury caused by physical means with disruption of normal continuity of structures.
a.trauma
b.contusion
c.blast
d.wound

A

wound

37
Q

In contrast to humoral responses, this reaction contain predominantly mononuclear cells.
a.Type I hypersensitivity
b.Type II hypersensitivity
c.Type III hypersensitivity
d.Type IV hypersensitivity

A

Type IV hypersensitivity

38
Q

This implies further development and means that some of the organ is present but markedly reduced in size from normal.
a.Agenesis
b.Aplasia
c.Atresia
d.Atrophy

A

Aplasia

39
Q

This is a decrease in the amount of tissue after normal growth has been achieved.
a.Agenesis
b.Aplasia
c.Atresia
d.Atrophy

A

Atrophy

40
Q

This lesion is an indication of emaciation of the animal.
a.compensatory hypertrophy
b.serous atrophy of fat
c.disuse atrophy
d.denervation atrophy

A

Serous atrophy of fat

41
Q

In epithelial cells, the transition from normal columnar epithelial lining to squamous epithelial lining is a form of:
a.aplasia
b.dysplasia
c.hyperplasia
d.metaplasia

A

metaplasia

42
Q

If two genotypes are present in one individual, one of which came from a twin via the placenta, the condition is called:
a.Chimerism
b.Mosaicism
c.Heteroploidy
d.Euploidy

A

Chimerism

43
Q

Which of the following is not a characteristic of a benign tumor?
a.Structure is typical of the tissue of origin
b.Growth is purely expansive
c.Usually with scanty mitotic figures
d.It is not a dangerous form

A

It is not a dangerous form

44
Q

A mast cell sarcoma is of _______ origin.
a.Epithelial
b.Mesenchymal
c.Hemopoietic
d.Nervous

A

Mesenchymal

45
Q

An adenocarcinoma is of _______ origin.
a.Epithelial
b.Mesenchymal
c.Hemopoietic
d.Nervous

A

Epithelial

46
Q

The proper term for tumors of lymphocytes is _______.
a.Leukosis
b.Leukemia
c.Lymphosarcoma
d.Lymphomatosis

A

Lymphosarcoma

47
Q

All of the following are active products of mast cell sarcomas except:
a.Heparin
b.Histamine
c.Protease
d.Adrenaline

A

Adrenaline

48
Q

Which of the following is not considered a neoplasm?
a.Teratoma
b.Myxoma
c.Hamartoma
d.Chondroma

A

Hamartoma

49
Q

Acute multifocal necrotizing hepatitis is an example of a:
a.Clinical diagnosis
b.Definitive diagnosis
c.Morphologic diagnosis
d.Etiologic diagnosis

A

Morphologic diagnosis

50
Q

This is a type of necrosis that tends to develop at the distal aspect of extremities, such as the limbs, tail, or pinnae, or in dependent portions of organs, such as the mammary glands or lung lobes.
a.Coagulative
b.Caseous
c.Gangrenous
d.Liquefactive

A

Gangrenous