General Pathology Flashcards

0
Q

Autophagic granules is seen in where?

A

Atrophy

Intracytoplasmic vacuoles containing debris of degraded organelles

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1
Q

What is the deficiency of intrinsic factor?

A

Pernicious anemia

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2
Q

Organs where coagulative necrosis is seen?

A

Heart, kidneys

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3
Q

Organ where liquefactive necrosis is seen?

A

Brain

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4
Q

Caseous necrosis is seen in which condition?

A

Tuberculous granuloma

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5
Q

Wet gangrene is also known as?

A

Liqueafactive necrosis

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6
Q

Dry gangrene is also known as?

A

Coagulative necrosis

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7
Q

Enzymatic fat necrosis is seen in which condition?

A

Acute hemorrhagic pancreatitis

Soap formation

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8
Q

Examples of proapoptotis

A

Bax, Bac, p53

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9
Q

Bcl-2 is an?

A

Anti apoptosis

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10
Q

What is the wear and tear pigment?

A

Lipofuscin

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11
Q

What is the end product of membrane lipid perodixation?

A

Lipofusin

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12
Q

Granuloma with a horseshoe pattern is also known as?

A

Langherhans cells

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13
Q

Red infarcts are seen in which organs?

A

Lungs, gastrointestinal tract

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14
Q

White infarcts are seen in which organs?

A

Heart, spleen, kidney

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15
Q

Brown atrophy is described as?

A

Atrophy + Lipofuscin accumulation

16
Q

What are the Lines of Zhan?

A

Arterial thrombi

17
Q

Fat emboli are most commonly associated with?

18
Q

Caisson disease is seen in?

A

Divers who ascend quickly

Presence of small air emboli in the CNS, bones, and tissues

19
Q

Birbeck granules are seen where?

A

Langerhans cells of the skin

20
Q

These are tennis-racket shaped cytoplasmic granules

A

Birbeck granules

21
Q

HLA -B27 antigen is seen in which condition?

A

Ankylosing spondylitis

22
Q

Swiss type agammaglobulinemia is also known as?

A

Severe combined immunodeficiency disease (SCID)

AR form: Adenosine delaminates deficiency

23
Q

What condition presents with ataxia, confusion, ophthalmoplegia, and nystagmus?

A

Wernicke-Korsakoff Sydrome Alcoholic encephalopathy

Alcohol+Thiamine deficiency

24
Fanconi syndrome is associated with?
Lead There is impaired reabsorption of phosphate, glucose, AA Basophilic stippling of RBC Hypo-micro anemia: ALA dehydratase inhibition
25
Basophilic stippling of RBC is also seen in which condition?
Fanconi syndrome Hypo-micro anemia: ALA dehydratase inhibition
26
Liver changes associated with carbon tetrachloride
Centriloular necrosis and fatty change of the liver
27
Depigmented bands with pale streaking in the hair or skin is seen in which condition?
Kwashiorkor
28
Bitter almond smell is associate with which condition?
Cyanide poisoning
29
What is the hallmark of acute inflammation
Increased vascular permeability