General Pathology Flashcards

0
Q

Autophagic granules is seen in where?

A

Atrophy

Intracytoplasmic vacuoles containing debris of degraded organelles

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1
Q

What is the deficiency of intrinsic factor?

A

Pernicious anemia

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2
Q

Organs where coagulative necrosis is seen?

A

Heart, kidneys

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3
Q

Organ where liquefactive necrosis is seen?

A

Brain

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4
Q

Caseous necrosis is seen in which condition?

A

Tuberculous granuloma

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5
Q

Wet gangrene is also known as?

A

Liqueafactive necrosis

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6
Q

Dry gangrene is also known as?

A

Coagulative necrosis

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7
Q

Enzymatic fat necrosis is seen in which condition?

A

Acute hemorrhagic pancreatitis

Soap formation

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8
Q

Examples of proapoptotis

A

Bax, Bac, p53

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9
Q

Bcl-2 is an?

A

Anti apoptosis

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10
Q

What is the wear and tear pigment?

A

Lipofuscin

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11
Q

What is the end product of membrane lipid perodixation?

A

Lipofusin

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12
Q

Granuloma with a horseshoe pattern is also known as?

A

Langherhans cells

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13
Q

Red infarcts are seen in which organs?

A

Lungs, gastrointestinal tract

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14
Q

White infarcts are seen in which organs?

A

Heart, spleen, kidney

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15
Q

Brown atrophy is described as?

A

Atrophy + Lipofuscin accumulation

16
Q

What are the Lines of Zhan?

A

Arterial thrombi

17
Q

Fat emboli are most commonly associated with?

A

Fractures

18
Q

Caisson disease is seen in?

A

Divers who ascend quickly

Presence of small air emboli in the CNS, bones, and tissues

19
Q

Birbeck granules are seen where?

A

Langerhans cells of the skin

20
Q

These are tennis-racket shaped cytoplasmic granules

A

Birbeck granules

21
Q

HLA -B27 antigen is seen in which condition?

A

Ankylosing spondylitis

22
Q

Swiss type agammaglobulinemia is also known as?

A

Severe combined immunodeficiency disease (SCID)

AR form: Adenosine delaminates deficiency

23
Q

What condition presents with ataxia, confusion, ophthalmoplegia, and nystagmus?

A

Wernicke-Korsakoff Sydrome Alcoholic encephalopathy

Alcohol+Thiamine deficiency

24
Q

Fanconi syndrome is associated with?

A

Lead

There is impaired reabsorption of phosphate, glucose, AA
Basophilic stippling of RBC
Hypo-micro anemia: ALA dehydratase inhibition

25
Q

Basophilic stippling of RBC is also seen in which condition?

A

Fanconi syndrome

Hypo-micro anemia: ALA dehydratase inhibition

26
Q

Liver changes associated with carbon tetrachloride

A

Centriloular necrosis and fatty change of the liver

27
Q

Depigmented bands with pale streaking in the hair or skin is seen in which condition?

A

Kwashiorkor

28
Q

Bitter almond smell is associate with which condition?

A

Cyanide poisoning

29
Q

What is the hallmark of acute inflammation

A

Increased vascular permeability