General Pathology Flashcards
Autophagic granules is seen in where?
Atrophy
Intracytoplasmic vacuoles containing debris of degraded organelles
What is the deficiency of intrinsic factor?
Pernicious anemia
Organs where coagulative necrosis is seen?
Heart, kidneys
Organ where liquefactive necrosis is seen?
Brain
Caseous necrosis is seen in which condition?
Tuberculous granuloma
Wet gangrene is also known as?
Liqueafactive necrosis
Dry gangrene is also known as?
Coagulative necrosis
Enzymatic fat necrosis is seen in which condition?
Acute hemorrhagic pancreatitis
Soap formation
Examples of proapoptotis
Bax, Bac, p53
Bcl-2 is an?
Anti apoptosis
What is the wear and tear pigment?
Lipofuscin
What is the end product of membrane lipid perodixation?
Lipofusin
Granuloma with a horseshoe pattern is also known as?
Langherhans cells
Red infarcts are seen in which organs?
Lungs, gastrointestinal tract
White infarcts are seen in which organs?
Heart, spleen, kidney
Brown atrophy is described as?
Atrophy + Lipofuscin accumulation
What are the Lines of Zhan?
Arterial thrombi
Fat emboli are most commonly associated with?
Fractures
Caisson disease is seen in?
Divers who ascend quickly
Presence of small air emboli in the CNS, bones, and tissues
Birbeck granules are seen where?
Langerhans cells of the skin
These are tennis-racket shaped cytoplasmic granules
Birbeck granules
HLA -B27 antigen is seen in which condition?
Ankylosing spondylitis
Swiss type agammaglobulinemia is also known as?
Severe combined immunodeficiency disease (SCID)
AR form: Adenosine delaminates deficiency
What condition presents with ataxia, confusion, ophthalmoplegia, and nystagmus?
Wernicke-Korsakoff Sydrome Alcoholic encephalopathy
Alcohol+Thiamine deficiency
Fanconi syndrome is associated with?
Lead
There is impaired reabsorption of phosphate, glucose, AA
Basophilic stippling of RBC
Hypo-micro anemia: ALA dehydratase inhibition
Basophilic stippling of RBC is also seen in which condition?
Fanconi syndrome
Hypo-micro anemia: ALA dehydratase inhibition
Liver changes associated with carbon tetrachloride
Centriloular necrosis and fatty change of the liver
Depigmented bands with pale streaking in the hair or skin is seen in which condition?
Kwashiorkor
Bitter almond smell is associate with which condition?
Cyanide poisoning
What is the hallmark of acute inflammation
Increased vascular permeability