CNS Flashcards

0
Q

Rabies most commonly affect which part of the brain?

A

Eosinophilic intracytoplasmic inclusion in the hippocampus and Purkinje cells

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1
Q

Negri bodies are found in which condition?

A

Rabies

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2
Q

Encephalitis associated with corneal transplantation

A

Creutzfeldt-Jakob disease

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3
Q

Albumino-cytologic dissociation is seen in which condition?

A

GBS

Increased protein concentration with modest increased in cell count

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4
Q

Hirano bodies are associated with what disease?

A

Alzheimer disease

Intracytoplasmic proximal denditic eosinophilic inclusion consisting of actin

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5
Q

What is condition is associated with the downward displacement of the cerebral tonsils and medulla through the foramen magnum?

A

Arnold-Chiari malformation

Associated with thoracolumbar meningomyelocele

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6
Q

What is the intracerebral hemorrhage secodnary to long standing hypertension?

A

Charcot-Bouchard aneurysm

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7
Q

Liquefactive necrosis is seen in which organ?

A

Infarction (Brain)

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8
Q

Subarachnoid aneurysm is secondary to?

A

Congenital berry aneurysm, usually at the bifurcation of MCA

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9
Q

Wernicke triad is composed of?

A

Confusion, ataxia, ophthalmoplegia

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10
Q

Which condition is associated with subcortical leukoencephalopathy, presenting with multiple lacunar infarcts with sparing of the cortex?

A

Binswanger disease

Associated with hypertension

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11
Q

Pick disease affects which parts of the brain?

A

Temporal and frontal lobes

Usually seen in women

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12
Q

Huntington disease affects which part of the brain?

A

Caudate nucleus and putamen

Autosomal dominant

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13
Q

It is also known as the “Idiopathic Parkinson disease”

A

Lewy bodies

Paralysis agitans
Eosinophilic intracytoplasmic inclusion

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14
Q

von Economo encephalitis is also known as?

A

Postencephalitic parkinsonism

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15
Q

Lou Gehrig disease is also known as which disease?

A

Amyotrophic lateral sclerosis (ALS)

16
Q

Parkinsonism + autonomic dysfunction + orthostatic hypotensio

A

Shy-Drager syndrome

17
Q

CAG trinucleotide repeats is associated with which condition?

A

Huntington disease

18
Q

Most common form of motor nueron disease ?

A

ALS

19
Q

Pseudopalisading arrangement of tumor cells is seen in which condition?

A

Glioblastoma multiforme

20
Q

Fried egg appearance is associated with which brain neoplasm?

A

Oligodendroglioma

21
Q

Ependymoma affects which part of the brain?

A

Fourth ventricle

Presents with tubules and rosettes

22
Q

Whorled pattern and psammoma bodies are seen in which condition?

A

Meningioma

Originates in arachnoidal cells

23
Q

Neurilemmoma is also known as?

A

Schwannoma

Antoni A: interlacing, palisading nueclie
Antoni B: looser

24
Q

Tumors of peripheral nerve (Schwann cells) are known as?

A

Neurofibroma

May be part of von Recklinghausen neurofibromatosis

25
Q

Herniation of suprasellar subarachnoid space through incomplete diaphragm sella

A

Empty sella syndrome

Seen in obese, multiparous women with headaches and HTN