CNS Flashcards

0
Q

Rabies most commonly affect which part of the brain?

A

Eosinophilic intracytoplasmic inclusion in the hippocampus and Purkinje cells

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1
Q

Negri bodies are found in which condition?

A

Rabies

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2
Q

Encephalitis associated with corneal transplantation

A

Creutzfeldt-Jakob disease

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3
Q

Albumino-cytologic dissociation is seen in which condition?

A

GBS

Increased protein concentration with modest increased in cell count

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4
Q

Hirano bodies are associated with what disease?

A

Alzheimer disease

Intracytoplasmic proximal denditic eosinophilic inclusion consisting of actin

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5
Q

What is condition is associated with the downward displacement of the cerebral tonsils and medulla through the foramen magnum?

A

Arnold-Chiari malformation

Associated with thoracolumbar meningomyelocele

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6
Q

What is the intracerebral hemorrhage secodnary to long standing hypertension?

A

Charcot-Bouchard aneurysm

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7
Q

Liquefactive necrosis is seen in which organ?

A

Infarction (Brain)

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8
Q

Subarachnoid aneurysm is secondary to?

A

Congenital berry aneurysm, usually at the bifurcation of MCA

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9
Q

Wernicke triad is composed of?

A

Confusion, ataxia, ophthalmoplegia

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10
Q

Which condition is associated with subcortical leukoencephalopathy, presenting with multiple lacunar infarcts with sparing of the cortex?

A

Binswanger disease

Associated with hypertension

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11
Q

Pick disease affects which parts of the brain?

A

Temporal and frontal lobes

Usually seen in women

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12
Q

Huntington disease affects which part of the brain?

A

Caudate nucleus and putamen

Autosomal dominant

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13
Q

It is also known as the “Idiopathic Parkinson disease”

A

Lewy bodies

Paralysis agitans
Eosinophilic intracytoplasmic inclusion

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14
Q

von Economo encephalitis is also known as?

A

Postencephalitic parkinsonism

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15
Q

Lou Gehrig disease is also known as which disease?

A

Amyotrophic lateral sclerosis (ALS)

16
Q

Parkinsonism + autonomic dysfunction + orthostatic hypotensio

A

Shy-Drager syndrome

17
Q

CAG trinucleotide repeats is associated with which condition?

A

Huntington disease

18
Q

Most common form of motor nueron disease ?

19
Q

Pseudopalisading arrangement of tumor cells is seen in which condition?

A

Glioblastoma multiforme

20
Q

Fried egg appearance is associated with which brain neoplasm?

A

Oligodendroglioma

21
Q

Ependymoma affects which part of the brain?

A

Fourth ventricle

Presents with tubules and rosettes

22
Q

Whorled pattern and psammoma bodies are seen in which condition?

A

Meningioma

Originates in arachnoidal cells

23
Q

Neurilemmoma is also known as?

A

Schwannoma

Antoni A: interlacing, palisading nueclie
Antoni B: looser

24
Tumors of peripheral nerve (Schwann cells) are known as?
Neurofibroma May be part of von Recklinghausen neurofibromatosis
25
Herniation of suprasellar subarachnoid space through incomplete diaphragm sella
Empty sella syndrome Seen in obese, multiparous women with headaches and HTN