General Anaesthetics Inhaled Flashcards
Examples of volatile liquid anaesthetics
isoflurane
desflurane
sevoflurane
MOA of volatile liquid anaesthetics
unknown
?act on GABA, glycine and NDMA receptors
adverse effects of volatile liquid anaesthetics
myocardial depression
malignant hyperthermia
halothane is hepatoxic - not used
what are volatile liquid anaesthetics used for?
induction and maintenance of anaesthesia
what is the mechanism of nitrous oxide?
unknown
?via a combination of NDMA, nACh, 5-HT3, GABAA and glycine receptors
what are the adverse effects of nitrous oxide?
May diffuse into gas-filled body compartments → increase in pressure.
Should therefore be avoided in certain conditions e.g. pneumothorax
when should nitrous oxide be avoided?
Should therefore be avoided in certain conditions e.g. pneumothorax
what is nitrous oxide used for?
Used for maintenance of anaesthesia and analgesia (e.g. during labour)