General Flashcards
What are liver functions
Metabolism (drugs, toxic products (eg: ammonia) Immunological Metabolic homeostasis Storage Bile production Biosynthesis (albumin, clotting factors)
What does liver function test include
Total bilirubin Conjugated bilirubin ALT AST ALP GGT Albumin
Symptoms of acute liver dysfunction
Abdominal pain Pruritus Lethargy Bruising/ bleeding Pale stool/ dark urine Weight loss/ malnutrition/ anorexia
Symptoms of chronic liver dysfunction
Jaundice Red palm Gynaecomastia Spider naevi Ascites Bleeding Splenomegaly Gastric varices Encephalopathy
What’s the order of most robust evidences
Lowest to highest
Ideas and opinion Case series and case reports Cross sectional studies Case control Cohort studies RCTs Sys reviews metanalysis
Where would you check for the childhood immunisation schedule
Green book
Following children’s immunisation what records should be updated
Red book (child Heath record) GP records
Should premature i facts have immunisations delayed
No
If a child is admitted with missed vaccination, what would you advise
Give them the vaccinations or encourage them to catch up ASAP
What metabolised codeine to morphine
Cyp2d6
Why’s aspiring contraindicated for under 16
Reye’s syndrome (brain and liver damage)
What resources would you would to see meds is safe in pregnancy and breastfeeding
Spc
BNF
Toxbase
Bumps
How do you work out the number of alcoholic units
% of alcohol by volume x liquid in mL
Divided by 1000
What’s the maximum units of alcohol
Men 21
Women 14
A high grade fever is a temperature above
40
