Chapter 7- GU System Flashcards
What treatment is available for urinary incontinence
Pelvic floor exercise is used
Drug treatments includes:
Duloxetine for stress associated incontinence
Antimuscarinic (Oxybutinin, solifenacin) and selective B3 receptor stimulation (mirabegron)
Side effects of Antimuscarinic used in urinary incontinence
Constipation
Dry mouth
Sweating
Dilation of pupils
What’s used for bedtime wetting (enuresis) in children
Observe fluid intake
Set alarms
Desmopressin if alarm not effective
Imipramine (in children)
How is acute urinary retention managed
Catheterisation used to relieve symptoms Alpha blocker (doxazosin, tamsulosin) given for atleast 2 days to manage the acute urinary retention
Treatment for chronic urinary retention
Alpha blocker (doxazosin, tamsulosin)
5- alpha reductase inhibitor (finesteride, dutasteride) especially if enlarged prostate
(Or both)
Then surgery
What’s the most common cause of urinary retention in men?
Benign prostatic hyperplasia
Side effects of alpha blockers
Depression Dry mouth GI disturbances Dizziness (may cause hypotension on first dose so take sitting) Impair motor skilled tasks (driving) Floppy iris syndrome
Why should cataracts be cautioned in orients having cataract surgery
It can give floppy iris syndrome risk
What must you counsel for 5-alpha reductase inhibitors
Women of child bearing age should avoid handling crushed or broken tablets/ leaking caps
Excreted in semen so use of condom is recommended
Chance of male developing breast cancer so changes in breast tissue should be reported immediately
What’s the most effective form of contraception
Hormonal
When can hormonal contraceptives be used
Women who have started their menstrual cycle
What’s does the combined hormonal contraceptives contain
Oestrogen and progesterone
Advantages of the CHC
Reliable and reversible
Reduced dysmenorrhea (pain) and menorrhagia (heavy bleeding)
Less ovarian cysts
Less benign breast disease
Less risk of ovarian and endometrial cancer
Reduced risk of pelvic inflammatory disease
What’s monophasic and phasic COC pill
Monophasic= contains the same amount of eostrogen and progesterone
Phasic= contains varying amount
How long before major elective surgery, leg surgery or surgery that results in immobilisation should oestrogen containing contraception be stopped
4 weeks
When should CHC be stopped immediately
Sudden sever chest pain Sudden breathlessness Unexplained swelling or pain in calf Severe stomach pain BP above 160/95mmHg Serious neurological effects Hapatitis/ jaundice
What should be given if oestrogen containing contraceptives are not indicated
Progesterone only contraceptives
When can emergency contraception be offered to a person
After unprotected sex taken place:
On any day of their cycle
21 days after childbirths
5 days after abortion, miscarriage
Regular contraception been compromised
What are the emergency hormonal contraception and how long they effective for
Copper IUD first line- 5 days
Levonorgestrel- 3 days LEVONELLE
Ulipristal- 5 days (if obese) ELLAONE
How long should women wait after taking ulipristal before starting regular hormonal contraception
5 days
When is the risk of VTE greater when patients on hormonal contraception
Family history of VTE under 45 Obese Immobilised Age over 35, avoid if over 50 Smoker History of superficial thrombophlebitis
What is considered a missed pill with hormonal contraception combined pill
More that 24 hours late
Worse at the beginning or end of the cycle
What’s another method of emergency contraception
Intra uterine device
Can be inserted upto 5 days after unprotected sex and acts as contraception after
What’s the risk of intra- uterine device
Risk of infection in the first 20 days after insertion and a carriage of STI
Can you breastfeed after taking emergency hormonal pill
Levonorgestrel = yes
Ulipristal = wait 1 week
What are the 3 types of progesterone only pill and when is it considered a missed pill
Levonorgestrel -3hrs late
Desogestrel- 12hrs late
Norethisterone -3 hours late
What’s a missed contraceptive pill counselling
Take one as soon as you remember, may mean taking 2 in 24hours
Use barrier method for the next 24hours
What are the different types of hormonal contraception, what do they contain and how long do they last
COC pill (oestrogen and progesterone) take one daily with 7 day free period
Contraceptive patch (oestrogen and progesterone) last one week
Contraceptive injection (progesterone) last 2-3 months
Contraceptive implant (progesterone) lasts upto 3 years
Intra-uterine device (progesterone)
What medicines do EHC interact with
Enzyme inducing drugs:
Rifampicin, anti-epileptic, St. John’s wort, ritonavir, griseofulvin
What can you do to the levonorgestrel 1.5mg EHC if the patient is on an enzyme inducing drug or is obese
Give double (3mg) unlicensed
Or a non hormonal emergency contraceptive (copper IUD)