Gene regulation Flashcards
1
Q
Polycistronic operons
A
Multiple sequences of DNA that each encode a polypeptide
2
Q
Repressor binds where?
A
To the operator
3
Q
Where does the activator go?
A
It interacts with the RNAP directly
4
Q
In the lac operon, what is the inducer?
A
Lactose
5
Q
In the lac operon, what is the co-activator?
A
cAMP
6
Q
Describe the structure of cholera toxin
A
Has seven subunits: A1 is the actual toxic part, A2 is part of the vehicle
7
Q
What does the A1 subunit do?
A
Modifies a G protein by ADP-ribosylation, activating adenylyl cyclase, which turns on efflux transporters and causes osmotic diarrhea
