Antibiotic resistance Flashcards
Describe bacterial virus genomes
Made of either RNA or DNA and can be either single- or double-stranded, linear or circular.
How many base pairs make up the typical bacteriophage genome?
3000-300,000
Describe what is included in a transposon.
Hybrid of DNA with virulence factor in the middle and flanked by insertion sequences
What is it called when a bacterium is able to pick up naked DNA?
Competence
How is the DNA taken up into the cell?
One strand is degraded while the other one is taken into the cell
Three fates of transformed DNA
Degradation
Plasmid placement
Integration into the chromosome
Recombination
Incorporation of the exogenote into the genome of the bacterium
oriT
Origin of transfer
How is DNA resynthesized during conjugation?
In a rolling mechanism
Why are R plasmids so bad?
Multiple drug resistances can be carried on a single plasmid, and they can be transferred not only to the same species, but similar species and other members of the family.