Bacterial growth and nutrition Flashcards
Gyrase in bacteria
Needed to successfully complete DNA replication; target of antibiotics
Ribosomes in bacteria
Have the same role as eukaryotic ribosomes, but function differently
How is transcription and translation different in bacteria?
They are all done together right next to the DNA; no separate compartments
Peptidoglycan synthesis
Synthesized first as subunits in the cytoplasm then transferred across the membrane by a carrier molecule. Cross-linked to the already present peptidoglycan
Polymixins
Targets the cell membrane
How does knowledge of metabolism provide useful understanding of bacterial pathogenesis and its treatment?
Knowing its requirements for energy determine its preferred environment and can predict where infection will occur.
Can recognize pathogens by their preferred environment.
Can determine antibiotics based on metabolic features
Siderophores
Molecules that leave the bacterium to sequester iron and bring it back to the cell
What does adding H2O2 to a wound do?
Overwhelms the bacterial cells undergoing aerobic respiration since they already have a lot a free radicals in the cell