GCSE Infection and Response Flashcards

1
Q

What is a pathogen?

A

A harmful microorganism that can pass communicable diseases through organisms

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2
Q

Define ‘communicable’

A

A disease that can be passed from one organism to another

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3
Q

Define ‘infectious’

A

A pathogen that is highly transmittable

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4
Q

What are the four types of pathogen?

A

Virus, bacteria, fungi, protist

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5
Q

What is a virus made up of?

A

Nucleus acid and protein coat

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6
Q

What are bacterium made up of?

A

Nucleoid cell wall, cytoplasm and cell membrane

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7
Q

What are protists made up of?

A

Cell wall, cell membrane, nucleus, mitochondria, cytoplasm

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8
Q

What are fungi made up of?

A

Cell wall, cell membrane, nucleus, mitochondria, cytoplasm

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9
Q

List some modes of transmission

A

Inhalation of droplets, contact of bodily fluids, food, water, vectors (insects))

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10
Q

What does a primary defense do?

A

Prevents the movement of pathogens into the bloodstream. It targets all pathogens

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11
Q

List primary defenses

A

Mucus membrane, eyes (lyzoenzymes), stomach acid, playlets, skin

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12
Q

What do phagocytes do?

A

Engulfs pathogens through phagocytosis

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13
Q

What do lymphocytes do?

A

Produces antibodies to fit to antigens and stick them together for phagocytosis

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14
Q

How do white blood cells know what to attack?

A

They identify antigens as self or foreign

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15
Q

Define vaccination

A

A substance that is used to stimulate the production of antibodies and provide immunity against an infectious disease. It kick-starts the primary immune response

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16
Q

Give three ways antibiotics can kill bacteria

A

Distrusting cell wall synthesis, protein synthesis and the way DNA is replicated

17
Q

How does antibiotic resistance occur?

A

Misuse of antibiotics causing only mutated resistant bacteria to survive and spread, becoming the dominant strain of the bacterium

18
Q

What is MRSA?

A

A strain of S. aureus that has become resistant to certain antibiotics

19
Q

Name three antibiotics MRSA is resistant to

A

Methicillin, erythromycin, ciprofloxacin

20
Q

What makes a good medicine?

A

Must be effective, safe and stable

21
Q

Define placebo

A

A replica medicine

22
Q

Define blind trial

A

A trial where the patient doesn’t know if they’re getting the real drug or not

23
Q

Define double blind trial

A

A trial where neither the patient nor the doctor knows whether they’re getting the real drug or not

24
Q

What is a monoclonal antibody?

A

Identical antibodies made from mouse spleen cells and myeloma (cancer) cells

25
What is myeloma?
Cancer of white blood cells in bone marrow
26
What is a hybridoma?
A monoclonal antibody-producing cell made of mouse spleen cells and myeloma cells
27
Why are monoclonal antibodies useful?
They only bind to target molecules, making location and extraction of those molecules easie
28
What can the constant region be used for?
Binding things like coloured dye, drugs or radioactive isotopes for targeted treatment
29
How are plant diseases spread?
Air, sap, insects, pollen/seeds, physical contaxt
30
What are the key features of TMV?
Mosaic shapes discolouration on leaves, destroying chlorophyll and slowing down photosynthesis causing stunted growth
31
What are the key feature of rose black spot?
Purple/black discolouration on leaves causing them to drop off. This destroys chlorophyll and stops photosynthesis, causing stunted growth
32
How do plants absorb magnesium?
Through active transport in the roots
33
What do plants need magnesium for?
To create chlorophyll for photosynthesis
34
What are the symptoms of chlorosis?
Yellow leaves, stunted growth
35
What do plants need nitrates for?
Protein synthesis (growth + repair)
36
Give some common symptoms of diseased plants
Stunted growth, spots/malformation of leaves, discolouration, areas of decay, pests