Gastrointestinal Hormones

Question 1

Where is gastrin produced from

Answer 1

G cells of the antrum of the stomach

Question 2

Function of gastrin?

Answer 2

Produced by vagus nerve

Increases acid secretion by gastric parietal cells,
pepsinogen
and IF

increases gastric motility,
stimulates parietal cell maturation

Question 3

Where is CKK produced from ?

Answer 3

I cells of the small intestine

Question 4

Function of CKK?

Answer 4

Contracts the gall bladder

Induces satiety - decreases gastric emptying,

Increases secretion of enzyme-rich fluid from pancreas,

Question 5

Secretin is produced by

Answer 5

S cells in upper small intestine

Question 6

Function of secretin ?

Answer 6

Increases secretion of bicarbonate-rich fluid from pancreas and hepatic duct cells, decreases gastric acid secretion,

Question 7

What produces VIP ?

Answer 7

Small intestine, pancreas

Question 8

Function VIP?

Answer 8

Stimulates secretion by pancreas and intestines

inhibits acid secretion

Question 9

What produces Somatostatin

Answer 9

D cells in the pancreas and stomach

Question 10

Function of somatostatin ?

Answer 10

Decreases acid and pepsin secretion, decreases gastrin secretion,
decreases pancreatic enzyme secretion,
decreases insulin and glucagon

Question 11

refractory dyspepsia, diarrhoea, multiple duodenal ulcerations

Answer 11

Zollinger-Ellinson syndrome caused by a gastrin-secreting tumour (gastrinoma)