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Clinical Medication: HEENT > Gastroenterology > Flashcards

Gastroenterology Flashcards

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1
Q

Barrets esophagitis changes in cell type

A

changes from squamous epithelium to columnar epithelium

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2
Q

what is the first line treatment for mild and severe GERD?

A

mild is a h2

severe is a ppi

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3
Q

what medications decrease the lower esophageal sphincter pressure and thus increase GERD, should be avoided?

A

B2 agonist, CCB, Nitrates, alpha adrenergic antagonistic, anticholinergics, theophyline, morphine

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4
Q

what are the clinical findings of infectious esophagitis?

A

Idynophagia (pain) or dysphagia in an immunosupressed patient

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5
Q

what are the common causes of infectious esophagitis and how to treat?

A

Fungal: Candida–> Fluconazole
Viral: CMV–> Ganciclovir
HPV–>Acyclovir

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6
Q

What are the endoscopy findings of infectious esophagitis?

A

Deep or shallow ulcers depending on the infection

Yeast will have white curds.

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7
Q

pt has difficulty with both liquids and solids after a injury or disease on the brain stem or CN of swallowing

A

Neruogenic Dysphagia

Tx: Focused on the underlying cause

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8
Q

Patient has regurgitation of undigested food and liquid into the pharynx several hours after swallowing

A

Zenkers Diverticulum, caused by out pouching of the posterior hypopharynx

tx medically with agents that relax the esophagus like CCB, Nitrites, botylinum or surgically with resection.

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9
Q

Patient has dysphagia with solid foods

A

Esophageal stenosis
Progressive: rings/webs: dilation
Quickly: Malignancy: rection

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10
Q

Patient has slowly progressive chest pain, and episodic regurgitation with chest pain

A

Achalasia it is a global esophageal motor disorder with increased sphincter tone and decreased peristalsis.

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11
Q

Patient has dysphagia or intermittent chest pain that may or may not be associated with eating

A

Diffuse esophageal dysphagia

tx medically with agents that relax the esophagus like CCB, Nitrites, botylinum or surgically with resection.

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12
Q

what labs are used for dx of esophogeal motility disorders

A

Barium swallow, pharyngoscopy, and esophageal manometry

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13
Q

is esophageal cancer likely to met?

A

Yes because esophagus has no serosal layer so it mets easily into the mediastinum

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14
Q

Parrots beaked on barrium swallow

A

Achalasia

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15
Q

Patient has progressive dysphagia with marked weight loss, heart burn, vomiting and hoarseness of voice.

A

Esophageal neoplasms

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16
Q

Mallory Weiss tears?

A

Linear tears in the esophagus generally at the gastroesophageal junction that occurs with forceful vommiting or retching causing hematemeisis

Tx: usually go away on their own can use endoscopy cautary

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17
Q

Most common cause of esophageal Varicies?

A

Portal HTN caused by Cirrhosis

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18
Q

Budd Chiari disease?

A

thrombotic or non thrombotic obstruction of the hepatic vein can cause esophageal varicies

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19
Q

Known Cirrhosis with hematemesis

A

Esophageal Varicies

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20
Q

how to treat esophageal varicies?

A

life threatening, fluid replacement, pressors.

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21
Q

Type A v Type B gastritis?

A

Type A: genetic componet, autoimune (Pernicious anemia)

TypeB: Caused by pathogens most commonly HP , can also be NSAIDS or ETOH

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22
Q

How does pErnicious anemia cause gastrits?

A

Autoimmune distorder of the parietal cells which cause the gastritis, but it also inhibits the production of intrinsic facor which is needed for vit B 12 absorption (megaloblastic anemia)

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23
Q

How do NSAIDS cause gastritis?

A

decreased the amount of prostaglandin production in the stomach.

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24
Q

HP gastritis is likely to occur in what part of the stomach

A

antrum and body

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25
Dyspepsia and abdominal pain....
Gastritis PUD
26
how do you dx a spiral shaped bacillus gastritis?
This is HP. you use a urea breath test, because urea is from the break down of bacteria. you can also use fecal urea test or anigen testing for HP.
27
what are the most common cuases of gastritis
HP, NSAIDS, Pernicious Anemia, ETOH, Stress
28
what is dyspepsia (belching, bloating) abdominal pain that is burning or gnawing that often radiates to the back and either weight gain or anorexia dt?
PUD. The weight gain makes you think its a duodeum ulcer, which the pain improves with food where anorexia would make you think a gastric ulcer where the pain is worse with food.
29
Is PUD associated with cancer?
Yes, gastric uclers and HP are highly associated with gastric ademonas
30
what is the treatment for PUD?
A 14 day dose of PPI, Clarithromycin and amox. then cont the patient on the PPO
31
how do you test for PUD?
Endoscopy looking for the ulcers, history of use of NSAIDS or ETOH or a urea breath test for HP
32
what is Zollinger Ellison syndrome?
A gastrin secreating tumor (Gastrinoma) causing hypergastremia which results in PUD
33
What is the most common locations of a gastrinoma?
Pancreas or duodeum
34
What are the clinical features of Zollinger Ellison Syndrome?
It is clinically identical to PUD ( dyspepsia, abdominal pain that radiates to the back) but it has associated secretory diarrhea which is improved with PPI or H2 use. it also has melina leading to anemia.
35
how do you test for a ZES?
A fasting Gastrin >150 Secretin test >200 and endoscopy
36
pt with dyspepsia, weight loss, iron def anemia over the age of 40
Gastric Adenocarcimoma.
37
what is the patho of irritable bowel sydrome?
unknown, but they think it is a combination of altered motility hypersensitivity to intestinal distention and psychological distress
38
Patient with pain that is worse with food and releved with defication, has a combination of constipation and diarrhea. normal lab test and stool sample, negative colonoscopy? how do you treat this person
Irritable bowel syndrome Treat reasurrance, high fiber diet, bulking agents, antispazmetics and antihiahreals.
39
Patient with colicky epigastric/ RUQ pain stead and increase in intensity, occurs often after high fat meals, N/V possibly right scapular pain... dx: tx:
Labs: Bilirubin levels will increase, leukocytosis US HIDA ERCP Treatment sxr ACUTE CHOLECYTITIS
40
what is the triad for acute chollangitis and how will the patient present?
Triad: RUQ pain, Jaundice, Fever This is a potentially deadly condition of common bile duct obstruction combinded with asendingi nfection of ecoli/enterococcus/ kelb Treatment is ABX drain or sxr
41
how do you diagnose hepatitis?
Aminotrnsferase elevations are seen in each type of hepatitis. this indicae hepatic intercell damage.
42
Patients presents with Tenesumus, blood and pus filled diarrhea, and mild to no abdominal pain (if present in the LLQ) dx: test: treat
Dx: UC Colonoscopy/sigmoidoscopy starts at the rectum and continues proximally smoking is actually preventative in UC. SXR is a curative can use aminosalicylates and steriods
43
patient under the age of 40 presents with severe abdominal pain and bloody diarrhea. Dx: Test: Treat:
Dx: Crohns Colonoscopy starts anywhere in the GI tract from the mouth to the anus, mainly on the right side. Treatment: Acute: Steriods NPO Chronically: Diet (Elementary diet) Mesalamine, SMOKING cessation is critical to decrease the severity and quantity of attacks.
44
where is the GI affected: Crohns UC
Crohns: From mouth to anus mostly on the right side UC: starts at the rectum and move proximally (Left side
45
what is the presenting symptoms Crohns UC
Crohns: ABD pain, bloody diarrhea (under 40) UC: bloody and pus filled diarrhea.
46
Pt with inflamation of the SB with gluten containing foods?
Dx: Celiacs- | DX test: IgA antiendomysial and antitissue transglutamine blood test.
47
what is the triad of chronic pancreatitis?
DM ABD PAIN Malabsorption
48
what is the ransons criteria?
Age >55, Leukoctues >16000 LDH >400 Glu> 200 prognostics of Pancreatitis
49
what is the most sensitive way to diagnose an ulcer in Peptic ulcer diease?
Endoscopy
50
what is the treatment for H. Pylori induced ulcer?
PPI, Amoxicillin, and clarithromycin
51
if a patient has a colonoscopy with an polyp, which is removed when should he receive his next colonsocpy?
In 3 years. every 3 years after adeoma is removed
52
what are the classical signs of Portal hypertention?
Think the liver is fibrotic, so the hepatic vein can not drain fluid proximally, what comes off the hepatic vein. Slenomegaly, Hemorrhoids, testicular atrophy, acities, caput medusa, pulmar erythemia, and spider andiomas.
53
what are some lab test for portal hypertention?
Decreased Albumin, increased billirubin
54
what is the formula used on paracentesis of acities fluid to determine if its from portal hypertention or an inflamatroy sorce?
Serum albumin- Acities albumin if greater 1.1 then its portal hypertention. Inflammatory causes will have a ratio under 1.1 meaning the serum and acites fluid have similar amounts of albumin, this is because the vessels become leaky and cause protien to leak out into the acities fluid (pancreatitis, TB peritonitis, Hepatoma)
55
what is the patho of hepatic encephalopathy.
ammonia comes from break down of protein, in a health individual the ammonia goes to the liver and is converted to urea. then the urea is excreted by the kidneys. but when the liver is not working well (cirrhosis, the body builds up the levels of ammonia, ammonia is able to cross the blood brain barrier, causing hepatic encephalopathy which is AMS. Patient will also get a non-rthythmic flapping tremor called asterixis.
56
what is used to decrease ammonia levels in the blood?
lactulose
57
new onset GERD in patients >___ warrants an EGD.
45
58
A 48 year old women presents with a chage in bowel habits and 10 lbs weight loss over the past 2 months, despite preserved appetite, she notices increased abdominal gas , particularly after fatty meals. The stools are malodorous and occur 2-3 times a day , NO rectal bleeding is noticed. the symptoms are less prominent when the patietn follows a clear liquid diet. what is the Dx, Biopsy results, Lab test, treatment
Lab: IgA antiendomysial antibodies and antitissue glutaminase Biopsy Villous atrophy and increase lymphocytes in the lamina propia of small bowel Dx: Celiacs disease Treatment: Diet free of gluten .
59
Sifnet cells on gastic biopsy?
Gastic cancer
60
Mucosal inflammation and Crypt abscesses on sigmoidoscopy?
UC
61
small curved gram negative bacteria in areas of intestinal metaplasia on gastric biopsy?
H pylori
62
what is the stool osmolarity formula and what can it tell you?
stool osmolarity- 2 (stool na+stool K) an osmolar gap greater than 125 suggest the diarrhea is caused my osmotically active particles in the stool such as laxative, lactose intolerance or ingestion of sorbitol containing foods.
63
what is Hemochromatosis
A disorder of iron storage that results in deposition of iron in parechyma cells of the ie the liver and skin. you will have hypepigmentation of the skin and a palpable liver edge. you can also develop DM due to iron deposition in the pancreas.
64
a 32 year old white women complains of abdominal pain on and off since the age of 17, she noticies abdominal bloating releved by defication as well as alternating diarrhea and constipation. She has no weight loss, GI bleeding or nocturnal diarrhea. Exam and labs and imaginig all normal, what is the inital approach to treat?
Recommend increase dietary fibers, PRN antispasmodics and follow up exam in 2 mo. IBS
65
development of Diarhea 5 days after abx? | how do you dx
Cdiff | Identification of C diff TOXIN in the stool.
66
the most common type of fatty liver disease caused by obesity is _____vascular fatty liver?
Macro!

Clinical Medication: HEENT (39 decks)

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